SCHEMBL29029016

SCHEMBL29029016

O=C(O)c1ccccc1-c1cccc(C2CCCCC2)c1C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 1/20 0.46
ALDH1A1 P00352 5/20 0.45
LMNA P02545 2/20 0.45
MAPT P10636 1/20 0.45
PTGDR2 Q9Y5Y4 1/20 0.44
BRS3 P32247 1/20 0.42
KMO O15229 1/20 0.42
L3MBTL1 Q9Y468 2/20 0.41
MYC P01106 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
ACMSD Q8TDX5 2/20 0.41
CAMKK1 Q8N5S9 2/20 0.41
CAMKK2 Q96RR4 2/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41
ALOX12 P18054 1/20 0.41
PTGS2 P35354 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8774864 0.89 PTGDR2 (0.48) ALDH1A1LMNAMAPTPTGDR2BRS3
Phthalic Acid SCHEMBL11407238 0.88 PTGDR2 (0.47) ALDH1A1LMNAMAPTPTGDR2KMO
SCHEMBL1705927 0.87 KMO (0.46) ALDH1A1LMNAMAPTPTGDR2KMO
Phthalic Acid SCHEMBL11409627 0.86 ALDH1A1 (0.47) ALDH1A1LMNAMAPTPTGDR2KMO
SCHEMBL11405090 0.85 ACMSD (0.44) ALDH1A1LMNAMAPTPTGDR2KMO
SCHEMBL4827148 0.84 ALDH1A1 (0.51) ALDH1A1LMNAMAPTPTGDR2BRS3
SCHEMBL17323537 0.84 KMO (0.51) ALDH1A1PTGDR2KMOL3MBTL1MEN1
SCHEMBL17323545 0.84 KMO (0.51) ALDH1A1PTGDR2KMOL3MBTL1MEN1
SCHEMBL17323530 0.84 KMO (0.51) ALDH1A1PTGDR2KMOL3MBTL1MEN1
SCHEMBL29804902 0.82 ACMSD (0.40) FOLH1ALDH1A1PTGDR2KMOACMSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113493689-B Liquid crystal compound containing difluoromethoxy bridge bond and preparation method and application thereof 北京八亿时空液晶科技股份有限公司 2023-06-02 CN disclosed