Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PPARD | Q03181 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24804436 | 0.84 | CYP19A1 (0.54) | CYP19A1ALOX5PTGS2SMPD1PTPN1 | |
| SCHEMBL28588510 | 0.81 | CYP19A1 (0.56) | CYP19A1PPARGPPARDPPARAALOX5 | |
| SCHEMBL10635768 | 0.77 | CYP19A1 (0.43) | CYP19A1PPARGPPARDPPARAALOX5 | |
| SCHEMBL8699343 | 0.74 | ALOX5 (0.50) | CYP19A1PPARGPPARDPPARAALOX5 | |
| SCHEMBL14700119 | 0.73 | PRKCE (0.51) | ALOX5PTGS2KDM4EUSP2CYP3A4 | |
| SCHEMBL16199920 | 0.72 | CYP19A1 (0.72) | CYP19A1PPARGPPARAALOX5PTGS2 | |
| SCHEMBL21864136 | 0.71 | PPARG (0.58) | CYP19A1PPARGPPARDPPARAALOX5 | |
| SCHEMBL25759920 | 0.71 | MAOB (0.50) | ALOX5PTGS2KDM4ECYP3A4BCHE | |
| SCHEMBL16199995 | 0.71 | ALOX5 (0.54) | CYP19A1PPARGPPARAALOX5PTGS2 | |
| SCHEMBL17210403 | 0.71 | PRKCE (0.51) | CYP19A1ALOX5PTGS2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0118794-B1 | CHROMENE DERIVATIVES | ALKALOIDA VEGYéSZETI GYáR (HU) | 1988-02-10 | — | — | EP | disclosed |
| EP-0208147-A2 | Chromene derivatives, their preparation and their use as parasiticides | ALKALOIDA VEGYéSZETI GYáR (HU) | 1987-01-14 | — | — | EP | disclosed |