Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.56 |
| ▸ | DRD4 | P21917 | 6/20 | 0.56 |
| ▸ | DRD3 | P35462 | 6/20 | 0.56 |
| ▸ | DRD1 | P21728 | 3/20 | 0.56 |
| ▸ | DRD5 | P21918 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6954907 | 0.90 | CYP4F2 (0.48) | DRD2DRD4DRD3DRD1DRD5 | |
| SCHEMBL10664848 | 0.88 | DRD2 (0.51) | DRD2DRD4DRD3DRD1DRD5 | |
| SCHEMBL10636286 | 0.85 | DRD2 (0.51) | DRD2DRD4DRD3DRD1DRD5 | |
| SCHEMBL6355159 | 0.83 | CA2 (0.50) | — | |
| SCHEMBL10635876 | 0.81 | HTR6 (0.61) | DRD2DRD4DRD3DRD1DRD5 | |
| SCHEMBL17965962 | 0.80 | DRD2 (0.58) | DRD2DRD4DRD3DRD1DRD5 | |
| SCHEMBL9838425 | 0.80 | CYP4F2 (0.62) | DRD2DRD4DRD3DRD1DRD5 | |
| SCHEMBL9837746 | 0.80 | CYP4F2 (0.62) | DRD2DRD4DRD3DRD1DRD5 | |
| SCHEMBL1019684 | 0.80 | CYP4F2 (0.62) | DRD2DRD4DRD3DRD1DRD5 | |
| SCHEMBL29586758 | 0.80 | CYP4F2 (0.62) | DRD2DRD4DRD3DRD1DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4788214-A | ANTIALLERGENS | HOFFMAN-LA ROCHE INC. (US) | 1988-11-29 | — | — | US | disclosed |
| US-4785017-A | ANTIALLERGENS | HOFFMANN-LA ROCHE INC. (US) | 1988-11-15 | — | — | US | disclosed |