Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.32 |
| ▸ | GAPDH | P04406 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14307036 | 0.88 | HSD17B10 (0.41) | USP2CYP3A4CYP1A2CYP2C19 | |
| SCHEMBL9187817 | 0.82 | TSHR (0.43) | TSHRHPGDHTTMAPTMEN1 | |
| SCHEMBL355988 | 0.82 | USP2 (0.46) | TSHRHPGDHTTUSP2CYP3A4 | |
| SCHEMBL4948086 | 0.82 | USP2 (0.46) | TSHRHPGDHTTUSP2CYP3A4 | |
| SCHEMBL584131 | 0.81 | ALDH1A1 (0.30) | TSHR | |
| SCHEMBL10063300 | 0.78 | — | — | |
| SCHEMBL187210 | 0.78 | — | — | |
| SCHEMBL17787241 | 0.78 | — | — | |
| SCHEMBL13841296 | 0.77 | TSHR (0.42) | TSHRHPGDHTTMAPTMEN1 | |
| SCHEMBL1784666 | 0.77 | TSHR (0.50) | TSHRHPGDHTTMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160168190-A1 | C-20 STEROID COMPOUNDS, COMPOSITIONS AND USES THEREOF TO TREAT TRAUMATIC BRAIN INJURY (TBI), INCLUDING CONCUSSIONS | ORAGENICS, INC. | 2016-06-16 | — | — | US | disclosed |
| US-20150175650-A1 | SYNTHESIS OF ENT-PROGESTERONE AND INTERMEDIATES THEREOF | PREVACUS INC (US) | 2015-06-25 | — | — | US | disclosed |
| WO-2015095339-A1 | SYNTHESIS OF ENT-PROGESTERONE AND INTERMEDIATES THEREOF | PREVACUS, INC. (US) | 2015-06-25 | — | — | WO | disclosed |
| US-4766181-A | Silicone-modified polyester resin and silicone-sheathed polyester fibers made therefrom | UNION CARBIDE CORPORATION (US) | 1988-08-23 | — | — | US | disclosed |
| US-4758637-A | Silicone-modified polyester resin and silicone-sheathed polyester fibers made therefrom | UNION CARBIDE CORPORATION (US) | 1988-07-19 | — | — | US | disclosed |
| EP-0269023-A2 | Silicone-modified polyester resin and silicone-sheathed polyester fibers made therefrom | UNION CARBIDE CORPORATION (US) | 1988-06-01 | — | — | EP | disclosed |
| EP-0214658-A2 | Silicone-modified polyester resin and silicone-sheathed polyester fibers made therefrom | UNION CARBIDE CORPORATION (US) | 1987-03-18 | — | — | EP | disclosed |
| US-4640962-A | Silicone-modified polyester resin and silicone-sheathed polyester fibers made therefrom | UNION CARBIDE CORPORATION (US) | 1987-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150175650-A1 | SYNTHESIS OF ENT-PROGESTERONE AND INTERMEDIATES THEREOF | CYP21A2, PGR, CYP17A1 | TSHR 1309/4885HPGD 33/4885HTT 4257/4885 |
| US-20160168190-A1 | C-20 STEROID COMPOUNDS, COMPOSITIONS AND USES THEREOF TO TREAT TRAUMATIC BRAIN INJURY (TBI), INCLUDING CONCUSSIONS | CYP17A1, HSD17B7, FABP7 | TSHR 4014/4885HPGD 964/4885HTT 3440/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.