Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 9/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 5/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | GLA | P06280 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10637562 | 0.78 | XDH (0.42) | KDM4EHSD17B10ALDH1A1TSHRMAPK1 | |
| SCHEMBL10642519 | 0.73 | HTR7 (0.57) | KDM4EHSD17B10ALDH1A1GLACYP1A2 | |
| SCHEMBL11008112 | 0.66 | CA12 (0.59) | ALDH1A1TSHRPOLBKMT2A | |
| SCHEMBL9631092 | 0.66 | CA9 (0.59) | KDM4ETSHRHPGDGAAKMT2A | |
| SCHEMBL11014592 | 0.65 | ALDH1A1 (0.47) | KDM4EALDH1A1HPGDPOLBGAA | |
| SCHEMBL17485266 | 0.65 | KMT2A (0.56) | KDM4EHSD17B10ALDH1A1HPGDPOLB | |
| SCHEMBL10642521 | 0.65 | ALDH1A1 (0.45) | KDM4EHSD17B10ALDH1A1HPGDMAPK1 | |
| SCHEMBL30581253 | 0.63 | ALDH1A1 (0.69) | KDM4EHSD17B10ALDH1A1TSHRHPGD | |
| SCHEMBL4199990 | 0.63 | ALDH1A1 (0.69) | KDM4EHSD17B10ALDH1A1TSHRHPGD | |
| SCHEMBL10745767 | 0.61 | CA12 (0.61) | ALDH1A1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161498-B1 | PHENYLPIPERAZINE DERIVATIVES AND THEIR ACID ADDITION SALTS | MITSUBISHI KASEI CORPORATION (JP) | 1988-10-12 | — | — | EP | disclosed |
| US-4716161-A | HYPOTENSIVE AGENTS | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1987-12-29 | — | — | US | disclosed |
| EP-0161498-A1 | Phenylpiperazine derivatives and their acid addition salts | MITSUBISHI KASEI CORPORATION (JP) | 1985-11-21 | — | — | EP | disclosed |