Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10642077 | 0.91 | SLC6A2 (0.49) | SLC6A3SLC6A2RAB9AMAPTALDH1A1 | |
| SCHEMBL10641121 | 0.88 | SLC6A2 (0.53) | SLC6A3SLC6A2SLC6A4RAB9AMAPT | |
| SCHEMBL10640779 | 0.88 | NTSR1 (0.47) | SLC6A3SLC6A2RAB9AMAPTALDH1A1 | |
| SCHEMBL10642576 | 0.84 | SLC6A4 (0.51) | SLC6A4RAB9ASIGMAR1HRH3MAPT | |
| SCHEMBL10642942 | 0.84 | SLC6A3 (0.59) | SLC6A3SLC6A2SLC6A4RAB9ACHRM2 | |
| SCHEMBL10636817 | 0.82 | SLC6A3 (0.48) | SLC6A3SLC6A2SLC6A4CHRM2ADRA2B | |
| SCHEMBL10639658 | 0.82 | SLC6A3 (0.53) | SLC6A3SLC6A2SLC6A4RAB9AHRH3 | |
| SCHEMBL10637337 | 0.81 | SLC6A3 (0.57) | SLC6A3SLC6A2SLC6A4RAB9ACHRM2 | |
| SCHEMBL9224504 | 0.81 | ALDH1A1 (0.46) | SLC6A3SLC6A2RAB9ASIGMAR1ALDH1A1 | |
| SCHEMBL27306803 | 0.81 | ALDH1A1 (0.49) | SLC6A3SLC6A2RAB9AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0164853-B1 | (SUBSTITUTED-PHENYL)-5-OXO-2-PYRROLIDINEPROPANOIC ACIDS, A PROCESS FOR PRODUCING THE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE COMPOUNDS | WARNER-LAMBERT COMPANY (US) | 1988-07-06 | — | — | EP | disclosed |
| US-4584313-A | TREATING SENILITY | WARNER-LAMBERT COMPANY (US) | 1986-04-22 | — | — | US | disclosed |
| EP-0164853-A1 | (substituted-phenyl)-5-oxo-2-pyrrolidinepropanoic acids, a process for producing the compounds and pharmaceutical compositions comprising the compounds | WARNER-LAMBERT COMPANY (US) | 1985-12-18 | — | — | EP | disclosed |