Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | IDH2 | P48735 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3561446 | 0.80 | HPGD (0.31) | IDH2NOS1 | |
| SCHEMBL10641247 | 0.78 | LRRK2 (0.32) | IDH2 | |
| SCHEMBL10635292 | 0.74 | — | — | |
| SCHEMBL10635090 | 0.74 | HSP90AA1 (0.33) | — | |
| SCHEMBL10638806 | 0.71 | LMNA (0.37) | IDH2 | |
| SCHEMBL10639099 | 0.71 | PTPN1 (0.38) | — | |
| SCHEMBL2745624 | 0.67 | TLR8 (0.33) | NOS1 | |
| SCHEMBL10635259 | 0.66 | ALDH1A1 (0.32) | — | |
| SCHEMBL2773009 | 0.66 | NOS1 (0.36) | CA12CA1CA2CA4CA6 | |
| SCHEMBL10639089 | 0.66 | HSP90AA1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0114575-B1 | 2,4-DIAMINO-6-HALOGEN-5-TRIFLUOROMETHYL PYRIMIDINE WITH HERBICIDAL ACTIVITY | CIBA-GEIGY AG (CH) | 1988-02-03 | — | — | EP | claimed |
| US-4507146-A | PLANT GROWTH REGULATORS | CIBA-GEIGY CORPORATION (US) | 1985-03-26 | — | — | US | claimed |
| EP-0114575-A1 | 2,4-Diamino-6-halogen-5-trifluoromethyl pyrimidine with herbicidal activity | CIBA-GEIGY AG (CH) | 1984-08-01 | — | — | EP | claimed |
| EP-0114575-B1 | 2,4-DIAMINO-6-HALOGEN-5-TRIFLUOROMETHYL PYRIMIDINE WITH HERBICIDAL ACTIVITY | CIBA-GEIGY AG (CH) | 1988-02-03 | — | — | EP | disclosed |
| US-4507146-A | PLANT GROWTH REGULATORS | CIBA-GEIGY CORPORATION (US) | 1985-03-26 | — | — | US | disclosed |
| EP-0114575-A1 | 2,4-Diamino-6-halogen-5-trifluoromethyl pyrimidine with herbicidal activity | CIBA-GEIGY AG (CH) | 1984-08-01 | — | — | EP | disclosed |