Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 3/20 | 0.56 |
| ▸ | F2 | P00734 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10639380 | 0.87 | KDM4E (0.49) | GRIN2BF2KDM4EALDH1A1MAPT | |
| SCHEMBL4828216 | 0.87 | GRIN2B (0.61) | GRIN2BKDM4EALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL9854974 | 0.83 | ALDH1A1 (0.47) | GRIN2BF2KDM4EALDH1A1MAPT | |
| SCHEMBL17063265 | 0.83 | GRIN2B (0.57) | GRIN2BKDM4EALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL19475555 | 0.83 | GRIN2B (0.57) | GRIN2BKDM4EALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL10385453 | 0.83 | ALDH1A1 (0.58) | GRIN2BKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL10816215 | 0.83 | ALDH1A1 (0.44) | ALDH1A1MAPTHPGDLMNANPC1 | |
| SCHEMBL19782422 | 0.82 | GRIN2B (0.53) | GRIN2BF2KDM4EALDH1A1MAPT | |
| SCHEMBL29927194 | 0.82 | GRIN2B (0.55) | GRIN2BKDM4EALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL13713047 | 0.81 | SMN1; SMN2 (0.54) | GRIN2BF2KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4742052-A | Antibacterial β-lactam compounds | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1988-05-03 | — | — | US | disclosed |
| EP-0070204-B1 | CARBOXYLIC BETA-LACTAM COMPOUNDS AND THE PREPARATION THEREOF | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1987-11-19 | — | — | EP | disclosed |
| EP-0070204-A2 | Carboxylic beta-lactam compounds and the preparation thereof | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1983-01-19 | — | — | EP | disclosed |