Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.41 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.41 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | HPN | P05981 | 1/20 | 0.40 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4828216 | 0.86 | GRIN2B (0.61) | GRIN2BALDH1A1KDM4ENPSR1SMN1; SMN2 | |
| SCHEMBL17063265 | 0.85 | GRIN2B (0.57) | GRIN2BALDH1A1KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL19475555 | 0.85 | GRIN2B (0.57) | GRIN2BALDH1A1KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL10639596 | 0.82 | GRIN2B (0.56) | GRIN2BALDH1A1KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL29927194 | 0.81 | GRIN2B (0.55) | GRIN2BALDH1A1KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL10385453 | 0.81 | ALDH1A1 (0.58) | GRIN2BALDH1A1KDM4ETSHRNPSR1 | |
| SCHEMBL5452029 | 0.81 | GRIN2B (0.53) | GRIN2BALDH1A1KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL7350346 | 0.77 | BCL9 (0.48) | GRIN2BALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL29201731 | 0.77 | GRIN2B (0.53) | GRIN2BALDH1A1KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL180293 | 0.76 | ALDH1A1 (0.46) | GRIN2BALDH1A1KDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10196386-B2 | Compounds having muscarinic receptor antagonist and beta2 adrenergic receptor agonist activity | CHIESI FARMACEUTICI S.P.A. (IT) | 2019-02-05 | — | — | US | disclosed |
| US-20180016267-A1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARMACEUTICI S.P.A. (IT) | 2018-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180016267-A1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | ADRB2, ADRB1, ADRA2B | GRIN2B 388/4885ALDH1A1 1087/4885KDM4E 4716/4885 |
| US-10196386-B2 | Compounds having muscarinic receptor antagonist and beta2 adrenergic receptor agonist activity | ADRB2, ADRB1, ADRA2B | GRIN2B 388/4885ALDH1A1 1087/4885KDM4E 4716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.