Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GPR4 | P46093 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10639160 | 0.82 | SMN1; SMN2 (0.47) | ALDH1A1MAPTLMNASMN1; SMN2KMT2A | |
| SCHEMBL10805588 | 0.82 | ALDH1A1 (0.44) | ALDH1A1MAPTLMNASMN1; SMN2KMT2A | |
| SCHEMBL5724167 | 0.82 | ALDH1A1 (0.67) | ALDH1A1MAPTLMNASMN1; SMN2KMT2A | |
| SCHEMBL10639423 | 0.77 | ALDH1A1 (0.44) | ALDH1A1MAPTLMNASMN1; SMN2KMT2A | |
| SCHEMBL27640500 | 0.75 | SMN1; SMN2 (0.46) | ALDH1A1MAPTLMNASMN1; SMN2KMT2A | |
| SCHEMBL10639506 | 0.75 | ALDH1A1 (0.49) | ALDH1A1MAPTLMNASMN1; SMN2KMT2A | |
| SCHEMBL8587397 | 0.74 | ALDH1A1 (0.56) | ALDH1A1MAPTLMNASMN1; SMN2KMT2A | |
| SCHEMBL9519331 | 0.74 | ALDH1A1 (0.56) | ALDH1A1MAPTLMNASMN1; SMN2KMT2A | |
| SCHEMBL10639622 | 0.74 | SMN1; SMN2 (0.46) | ALDH1A1MAPTLMNASMN1; SMN2KMT2A | |
| SCHEMBL6046664 | 0.73 | ALDH1A1 (0.52) | ALDH1A1MAPTLMNASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4742052-A | Antibacterial β-lactam compounds | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1988-05-03 | — | — | US | disclosed |
| EP-0070204-B1 | CARBOXYLIC BETA-LACTAM COMPOUNDS AND THE PREPARATION THEREOF | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1987-11-19 | — | — | EP | disclosed |
| EP-0070204-A2 | Carboxylic beta-lactam compounds and the preparation thereof | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1983-01-19 | — | — | EP | disclosed |