Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10639160 | 0.83 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1LMNAMAPTHTR2A | |
| SCHEMBL9519331 | 0.81 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1LMNAMAPTRAB9A | |
| SCHEMBL8587397 | 0.81 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1LMNAMAPTRAB9A | |
| SCHEMBL6285052 | 0.81 | MEN1 (0.57) | SMN1; SMN2HTR2ARAB9AKMT2AMEN1 | |
| SCHEMBL10639622 | 0.79 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1LMNAMAPTHTR2A | |
| Hydrochloric Acid SCHEMBL27949581 | 0.79 | LMNA (0.53) | SMN1; SMN2ALDH1A1LMNAMAPTRAB9A | |
| SCHEMBL4488774 | 0.78 | ALDH1A1 (0.42) | SMN1; SMN2ALDH1A1LMNAMAPTHTR2A | |
| SCHEMBL9363980 | 0.78 | SMN1; SMN2 (0.52) | SMN1; SMN2ALDH1A1LMNAMAPTRAB9A | |
| SCHEMBL3039451 | 0.78 | KCNJ1 (0.53) | SMN1; SMN2ALDH1A1LMNAMAPTRAB9A | |
| SCHEMBL3039444 | 0.78 | SMN1; SMN2 (0.52) | SMN1; SMN2ALDH1A1LMNAMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1752074-A | Intermediate N-protection-(2S,4S)-2-[(3-hydroxyl carbonyl)-phenyl amino formyl)]-pyrrolidine-4-thio alcohol of ertabeinan | UNIV SHANGHAI JIAOTONG (CN) | 2006-03-29 | — | — | CN | disclosed |