Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | TGM2 | P21980 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 5/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10967103 | 0.91 | RAB9A (0.51) | RAB9ATGM2CTSLHDAC1HDAC2 | |
| SCHEMBL10967107 | 0.90 | RAB9A (0.50) | RAB9ATGM2CTSLMAPTL3MBTL1 | |
| SCHEMBL11475132 | 0.86 | ATM (0.53) | ATMCTSLHDAC1HDAC2 | |
| SCHEMBL10663207 | 0.85 | RAB9A (0.52) | RAB9ATGM2CTSL | |
| SCHEMBL11623831 | 0.84 | ATM (0.52) | RAB9ATGM2ATMCTSLMAPT | |
| SCHEMBL11066063 | 0.82 | ATM (0.66) | RAB9ATGM2ATMCTSLHDAC1 | |
| SCHEMBL11514580 | 0.82 | ATM (0.66) | RAB9ATGM2ATMCTSLHDAC1 | |
| SCHEMBL11518512 | 0.82 | ATM (0.69) | RAB9AATMCTSL | |
| SCHEMBL11514360 | 0.79 | RAB9A (0.51) | RAB9AMAPTL3MBTL1 | |
| SCHEMBL11692430 | 0.79 | ATM (0.49) | RAB9ATGM2ATMCTSLHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0071395-B1 | BETA-LACTAM ANTIBACTERIAL AGENTS | BEECHAM GROUP PLC (GB) | 1988-08-10 | — | — | EP | disclosed |
| US-4609652-A | FORMAMIDYL DERIVATIVES OF AMINO ACID DERIVATIVE ANTIBIOTICS | BEECHAM GROUP P.L.C. (GB) | 1986-09-02 | — | — | US | disclosed |
| US-4539149-A | β-Lactam antibacterial agents | BEECHAM GROUP P.L.C. (GB) | 1985-09-03 | — | — | US | disclosed |
| EP-0071395-A1 | Beta-lactam antibacterial agents | BEECHAM GROUP PLC (GB) | 1983-02-09 | — | — | EP | disclosed |