Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 4/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 7/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 7/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 7/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 7/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.36 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.36 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | TERT | O14746 | 1/20 | 0.35 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL15534411 | 0.80 | CHRNA7 (0.49) | CHRNA7HRH4 | |
| SCHEMBL10866344 | 0.79 | HDAC3 (0.41) | CHRNB2CHRNB4CHRNA3CHRNA4HRH4 | |
| SCHEMBL2418027 | 0.75 | HTR3E (0.61) | CHRNA7CHRNB2CHRNA4HTR7HTR6 | |
| SCHEMBL28241830 | 0.74 | TERT (0.62) | CHRNA7IP6K1TERT | |
| Hydrochloric Acid SCHEMBL15535527 | 0.73 | HTR3E (0.59) | CHRNA7CHRNB2CHRNA4HTR7HTR6 | |
| SCHEMBL10461264 | 0.73 | CHRNA7 (0.52) | CHRNA7HRH4HTR6 | |
| SCHEMBL10567250 | 0.73 | TERT (0.61) | CHRNA7IP6K1TERT | |
| SCHEMBL2253917 | 0.71 | KHK (0.47) | CHRNA7 | |
| SCHEMBL15543862 | 0.71 | NPC1 (0.46) | HRH4 | |
| SCHEMBL18101829 | 0.69 | NOTUM (0.56) | CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0169993-B1 | 7-(3-ARYL-1-PIPERAZINYL) AND 7-(3-CYCLOHEXYL-1-PIPERAZINYL) 3-QUINOLINE CARBOXYLIC ACIDS | BAYER AG (DE) | 1988-12-28 | — | — | EP | disclosed |
| EP-0169993-A3 | 7-(3-ARYL-1-PIPERAZINYL) AND 7-(3-CYCLOHEXYL-1-PIPERAZINYL) 3-QUINOLINE CARBOXYLIC ACIDS | — | 1986-03-26 | — | — | EP | disclosed |
| EP-0169993-A2 | 7-(3-Aryl-1-piperazinyl) and 7-(3-cyclohexyl-1-piperazinyl) 3-quinoline carboxylic acids | BAYER AG (DE) | 1986-02-05 | — | — | EP | disclosed |