Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 5/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 2/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.35 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.35 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 2/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10640449 | 0.79 | CHRNA7 (0.45) | HRH4IP6K1IP6K3IP6K2CHRNB2 | |
| SCHEMBL8727055 | 0.78 | HDAC3 (0.60) | HDAC3HDAC1HDAC2MGAMKCNH2 | |
| SCHEMBL15681572 | 0.78 | TERT (0.56) | HDAC3HDAC1HDAC2MGAMKCNH2 | |
| Hydrochloric Acid SCHEMBL15534244 | 0.77 | HDAC3 (0.59) | HDAC3HDAC1HDAC2MGAMKCNH2 | |
| SCHEMBL11014645 | 0.76 | MGAM (0.45) | HDAC3HDAC1HDAC2MGAMKCNH2 | |
| SCHEMBL10922894 | 0.71 | MGAM (0.49) | HDAC3HDAC1HDAC2MGAMKCNH2 | |
| SCHEMBL21835803 | 0.71 | CHEK1 (0.53) | HDAC3HDAC1HDAC2MGAMGAA | |
| SCHEMBL10888275 | 0.71 | IP6K1 (0.32) | HRH4IP6K1IP6K3IP6K2CHRNB2 | |
| SCHEMBL10619332 | 0.69 | HPGDS (0.41) | HDAC3HDAC1HDAC2MGAMHPGDS | |
| SCHEMBL10888292 | 0.69 | IP6K1 (0.32) | HRH4IP6K1IP6K3IP6K2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0169993-A2 | 7-(3-Aryl-1-piperazinyl) and 7-(3-cyclohexyl-1-piperazinyl) 3-quinoline carboxylic acids | BAYER AG (DE) | 1986-02-05 | — | — | EP | disclosed |