Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 7/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10673510 | 1.00 | GAA (0.35) | GAAALDH1A1KMT2AMAPTKDM4E | |
| SCHEMBL385064 | 0.90 | MAPT (0.43) | GAAALDH1A1KMT2AMAPTKDM4E | |
| SCHEMBL385065 | 0.90 | MAPT (0.43) | GAAALDH1A1KMT2AMAPTKDM4E | |
| SCHEMBL1397231 | 0.89 | ALDH1A1 (0.46) | ALDH1A1KMT2AMAPTMEN1TP53 | |
| SCHEMBL1397229 | 0.89 | ALDH1A1 (0.46) | ALDH1A1KMT2AMAPTMEN1TP53 | |
| SCHEMBL10640192 | 0.83 | MAPT (0.42) | GAAALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL10672787 | 0.83 | MAPT (0.42) | GAAALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL6704764 | 0.81 | RAB9A (0.39) | ALDH1A1KMT2AMAPTMEN1HPGD | |
| SCHEMBL6704762 | 0.81 | RAB9A (0.39) | ALDH1A1KMT2AMAPTMEN1HPGD | |
| SCHEMBL10673293 | 0.80 | MAPT (0.38) | GAAALDH1A1KMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0199672-B1 | OXIME SULPHONATES CONTAINING REACTIVE GROUPS | CIBA-GEIGY AG (CH) | 1988-06-01 | — | — | EP | disclosed |
| US-4736055-A | STARING MATERIAL FOR PHOTORESIST POLYMERS | CIBA-GEIGY CORPORATION (US) | 1988-04-05 | — | — | US | disclosed |
| EP-0199672-A1 | Oxime sulphonates containing reactive groups | CIBA-GEIGY AG (CH) | 1986-10-29 | — | — | EP | disclosed |