Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | DNM1 | Q05193 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1064301 | 1.00 | TSHR (0.47) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL1057338 | 1.00 | TSHR (0.47) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL1061078 | 1.00 | TSHR (0.47) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL3303123 | 1.00 | TSHR (0.47) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL3309655 | 1.00 | TSHR (0.47) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL3309565 | 1.00 | TSHR (0.47) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL1065998 | 1.00 | TSHR (0.47) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL4954370 | 1.00 | TSHR (0.47) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL1062564 | 1.00 | TSHR (0.47) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL3308656 | 1.00 | TSHR (0.47) | TSHRTHRBDNM1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7264653-B2 | Methods for inhibiting hydrate blockage in oil and gas pipelines using simple quaternary ammonium and phosphonium compounds | CHAMPION TECHNOLOGIES, INC. (US) | 2007-09-04 | — | — | US | claimed |
| WO-2005042675-A2 | METHODS FOR INHIBITING HYDRATE BLOCKAGE IN OIL AND GAS PIPELINES USING SIMPLE QUATERNARY AMMONIUM AND PHOSPHONIUM COMPOUNDS | CHAMPION TECHNOLOGIES, INC. (US) | 2005-05-12 | — | — | WO | claimed |
| US-20050081714-A1 | Methods for inhibiting hydrate blockage in oil and gas pipelines using simple quaternary ammonium and phosphonium compounds | HARBISON-FISCHER, INC. | 2005-04-21 | — | — | US | claimed |
| EP-2272800-B1 | Detoxification of water containing onium compounds | BAKER HUGHES INC (US) | 2015-01-21 | — | — | EP | disclosed |
| EP-2272800-A1 | Detoxification of water containing onium compounds | Baker Hughes Incorporated (US) | 2011-01-12 | — | — | EP | disclosed |
| US-7381689-B2 | Methods for inhibiting hydrate blockage in oil and gas pipelines using amide compounds | CHAMPION TECHNOLOGIES, INC. (US) | 2008-06-03 | — | — | US | disclosed |
| US-7264653-B2 | Methods for inhibiting hydrate blockage in oil and gas pipelines using simple quaternary ammonium and phosphonium compounds | CHAMPION TECHNOLOGIES, INC. (US) | 2007-09-04 | — | — | US | disclosed |
| EP-1766183-A1 | ENHANCEMENT MODIFIERS FOR GAS HYDRATE INHIBITORS | Baker Hughes Incorporated (US) | 2007-03-28 | — | — | EP | disclosed |
| WO-2005116399-A1 | ENHANCEMENT MODIFIERS FOR GAS HYDRATE INHIBITORS | BAKER HUGHES INCORPORATED (US) | 2005-12-08 | — | — | WO | disclosed |
| US-20050261529-A1 | Enhancement modifiers for gas hydrate inhibitors | BAKER HUGHES INCORPORATED | 2005-11-24 | — | — | US | disclosed |
| EP-1362160-B1 | COMPOSITION AND METHOD FOR INHIBITION OF FORMATION OF GAS HYDRATES | BAKER HUGHES INC (US) | 2005-09-28 | — | — | EP | disclosed |
| EP-1362160-A1 | COMPOSITION AND METHOD FOR INHIBITION OF FORMATION OF GAS HYDRATES | BAKER HUGHES INCORPORATED (US) | 2003-11-19 | — | — | EP | disclosed |
| US-6620330-B2 | Removing pollutants from waste water streams | BAKER HUGHES INCORPORATED | 2003-09-16 | — | — | US | disclosed |
| US-20030146173-A1 | Detoxification of quaternary onium compounds with polycarboxylate-containing compound | BAKER HUGHES INCORPORATED | 2003-08-07 | — | — | US | disclosed |
| US-6596911-B2 | Providing a mixture comprising water and a hydrocarbon; and contacting with onium compound and amine salt for inhibiting the formation of the hydrocarbon hydrates | BAKER HUGHES INCORPORATION | 2003-07-22 | — | — | US | disclosed |
| WO-2003051781-A1 | DETOXIFICATION OF QUATERNARY ONIUM COMPOUNDS WITH POLYCARBOXYLATE CONTAINING COMPOUND | BAKER HUGHES INCORPORATED (US) | 2003-06-26 | — | — | WO | disclosed |
| US-20030116507-A1 | Detoxification of onium compounds | BAKER HUGHES INCORPORATED | 2003-06-26 | — | — | US | disclosed |
| WO-2003051776-A2 | DETOXIFICATION OF WATER CONTAINING ONIUM COMPOUNDS | BAKER HUGHES INCORPORATED (US) | 2003-06-26 | — | — | WO | disclosed |
| WO-2002066785-A1 | COMPOSITION AND METHOD FOR INHIBITION OF FORMATION OF GAS HYDRATES | BAKER HUGHES INCORPORATED (US) | 2002-08-29 | — | — | WO | disclosed |
| US-20020038063-A1 | Composition and method for inhibition of formation of gas hydrates | BAKER HUGHES INCORPORATED | 2002-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261529-A1 | Enhancement modifiers for gas hydrate inhibitors | AQP1, API5, IWS1 | TSHR 4386/4885THRB 4687/4885DNM1 1232/4885 |
| US-20020038063-A1 | Composition and method for inhibition of formation of gas hydrates | HDHD5, SHH, NOTUM | TSHR 3951/4885THRB 2764/4885DNM1 1836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.