Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 17/20 | 1.00 |
| ▸ | CYP11B2 | P19099 | 17/20 | 1.00 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.62 |
| ▸ | FNTA | P49354 | 1/20 | 0.46 |
| ▸ | FNTB | P49356 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7694608 | 0.86 | CYP11B1 (0.75) | CYP11B1CYP11B2CYP19A1FNTAFNTB | |
| SCHEMBL8209046 | 0.85 | CYP11B1 (0.74) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL8139285 | 0.83 | CYP11B1 (0.71) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL1758083 | 0.81 | CYP11B1 (0.68) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL7700254 | 0.80 | CYP11B1 (0.67) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL8140959 | 0.80 | CYP11B1 (0.67) | CYP11B1CYP11B2CYP19A1FNTAFNTB | |
| SCHEMBL765399 | 0.80 | CYP11B1 (0.67) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL7986619 | 0.80 | CYP11B1 (0.67) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL7696780 | 0.80 | CYP11B1 (0.67) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL7499526 | 0.80 | CYP11B1 (0.68) | CYP11B1CYP11B2CYP19A1FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 157 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106640-A2 | N-BENZYL IMIDAZOLE DERIVATIVES | MAASTRICHT UNIVERSITY (NL) | 2009-09-03 | — | — | WO | claimed |
| EP-2095819-A1 | N-benzyl imidazole derivatives and their use as aldosterone synthase inhibitors | Maastricht University (NL) | 2009-09-02 | — | — | EP | claimed |
| US-20250114350-A1 | INHIBITORS OF PRENYLTRANSFERASES AS ANTIFUNGAL AGENTS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2025-04-10 | — | — | US | disclosed |
| US-20130289086-A1 | Aminopyrrolidinone Derivatives and Uses Thereof | DUGGAN MARK E (US) | 2013-10-31 | — | — | US | disclosed |
| US-20130289086-A1 | Aminopyrrolidinone Derivatives and Uses Thereof | DUGGAN MARK E (US) | 2013-10-31 | — | — | US | disclosed |
| US-20130289086-A1 | Aminopyrrolidinone Derivatives and Uses Thereof | DUGGAN MARK E (US) | 2013-10-31 | — | — | US | disclosed |
| US-8252829-B2 | Aminopyrrolidinone derivatives and uses thereof | LINK MEDICINE CORPORATION (US) | 2012-08-28 | — | — | US | disclosed |
| US-8252829-B2 | Aminopyrrolidinone derivatives and uses thereof | LINK MEDICINE CORPORATION (US) | 2012-08-28 | — | — | US | disclosed |
| US-8252829-B2 | Aminopyrrolidinone derivatives and uses thereof | LINK MEDICINE CORPORATION (US) | 2012-08-28 | — | — | US | disclosed |
| EP-2438059-A1 | AMINOPYRROLIDINONE DERIVATIVES AND USES THEREOF | Link Medicine Corporation (US) | 2012-04-11 | — | — | EP | disclosed |
| US-7943635-B2 | Benzylimidazolyl substituted 2-quinoline and quinazoline derivatives for use as farnesyl transferase inhibitors | JANSSEN PHARMACEUTICA NV (BE) | 2011-05-17 | — | — | US | disclosed |
| WO-1997036591-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1997-10-09 | — | — | WO | disclosed |
| WO-1997036593-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1997-10-09 | — | — | WO | disclosed |
| WO-1997036587-A1 | A METHOD OF TREATING CANCER | MERCK & CO., INC. (US) | 1997-10-09 | — | — | WO | disclosed |
| WO-1997036583-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1997-10-09 | — | — | WO | disclosed |
| WO-1997027853-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1997-08-07 | — | — | WO | disclosed |
| WO-1997027752-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1997-08-07 | — | — | WO | disclosed |
| WO-1996039137-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1996-12-12 | — | — | WO | disclosed |
| WO-1996037204-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1996-11-28 | — | — | WO | disclosed |
| WO-1996030343-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1996-10-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250114350-A1 | INHIBITORS OF PRENYLTRANSFERASES AS ANTIFUNGAL AGENTS | FNTA, FNTB, FDPS | CYP11B1 3101/4885CYP11B2 3669/4885CYP19A1 3254/4885 |
| US-20130289086-A1 | Aminopyrrolidinone Derivatives and Uses Thereof | PRMT1, PRMT5, AGTR2 | CYP11B1 91/4885CYP11B2 57/4885CYP19A1 833/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.