Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 12/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.43 |
| ▸ | FDPS | P14324 | 2/20 | 0.40 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.39 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10656066 | 0.83 | TBXAS1 (0.52) | TBXAS1EGLN3LMNA | |
| SCHEMBL17694460 | 0.81 | TBXAS1 (0.57) | TBXAS1 | |
| SCHEMBL7461666 | 0.80 | ALDH1A1 (0.50) | TBXAS1ALDH1A1EGLN3FDPS | |
| SCHEMBL17694458 | 0.80 | TBXAS1 (0.59) | TBXAS1ALDH1A1LMNA | |
| SCHEMBL28013740 | 0.80 | ALDH1A1 (0.53) | TBXAS1ALDH1A1EGLN3FDPSGGPS1 | |
| Hydrochloric Acid SCHEMBL28304957 | 0.79 | ALDH1A1 (0.48) | TBXAS1ALDH1A1EGLN3 | |
| Bromide SCHEMBL6435569 | 0.79 | ALDH1A1 (0.48) | TBXAS1ALDH1A1EGLN3FDPS | |
| SCHEMBL4793009 | 0.77 | ALDH1A1 (0.47) | TBXAS1ALDH1A1EGLN3 | |
| SCHEMBL16314611 | 0.77 | ALDH1A1 (0.50) | TBXAS1ALDH1A1EGLN3FDPS | |
| SCHEMBL9276891 | 0.76 | ALDH1A1 (0.46) | TBXAS1ALDH1A1EGLN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2693876-A1 | SUBSTITUTED METHYLFORMYL REAGENTS AND METHOD OF USING SAME TO MODIFY PHYSICOCHEMICAL AND/OR PHARMACOKINETIC PROPERTIES OF COMPOUNDS | Sphaera Pharma Pte. Ltd (SG) | 2014-02-12 | — | — | EP | claimed |
| WO-2012137225-A1 | SUBSTITUTED METHYLFORMYL REAGENTS AND METHOD OF USING SAME TO MODIFY PHYSICOCHEMICAL AND/OR PHARMACOKINETIC PROPERTIES OF COMPOUNDS | SPHAERA PHARMA PVT. LTD (IN) | 2012-10-11 | — | — | WO | claimed |
| EP-0195116-B1 | COMPOUND HAVING ANTIBACTERIAL AND ANTIMYCOTIC ACTIVITIES, PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT | ISTITUTO FARMACO BIOLOGICO RIPARI GERO S.r.l. (IT) | 1988-11-17 | — | — | EP | claimed |
| EP-0195116-A2 | Compound having antibacterial and antimycotic activities, preparation thereof and pharmaceutical compositions containing it | ISTITUTO FARMACO BIOLOGICO RIPARI GERO S.r.l. (IT) | 1986-09-24 | — | — | EP | claimed |
| EP-0195116-B1 | COMPOUND HAVING ANTIBACTERIAL AND ANTIMYCOTIC ACTIVITIES, PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT | ISTITUTO FARMACO BIOLOGICO RIPARI GERO S.r.l. (IT) | 1988-11-17 | — | — | EP | disclosed |
| EP-0195116-A2 | Compound having antibacterial and antimycotic activities, preparation thereof and pharmaceutical compositions containing it | ISTITUTO FARMACO BIOLOGICO RIPARI GERO S.r.l. (IT) | 1986-09-24 | — | — | EP | disclosed |
| US-4381307-A | Soft tertiary amine esters of bio-affecting carboxylic acids | MERCK & CO., INC. (US) | 1983-04-26 | — | — | US | disclosed |
| EP-0051278-A1 | Soft tertiary amine esters of bio-affecting carboxylic acids, processes for preparing and a pharmaceutical composition containing the same | MERCK & CO. INC. (US) | 1982-05-12 | — | — | EP | disclosed |