Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 10/20 | 0.45 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | WRN | Q14191 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10072238 | 0.83 | TBXAS1 (0.59) | ALDH1A1TBXAS1EGLN3 | |
| SCHEMBL7461666 | 0.81 | ALDH1A1 (0.50) | ALDH1A1TBXAS1EGLN3 | |
| SCHEMBL3690128 | 0.81 | TBXAS1 (0.53) | ALDH1A1TBXAS1ABL1RIN1 | |
| SCHEMBL28013740 | 0.81 | ALDH1A1 (0.53) | ALDH1A1TBXAS1EGLN3 | |
| Hydrochloric Acid SCHEMBL28304957 | 0.80 | ALDH1A1 (0.48) | ALDH1A1TBXAS1EGLN3 | |
| Bromide SCHEMBL6435569 | 0.80 | ALDH1A1 (0.48) | ALDH1A1TBXAS1EGLN3 | |
| SCHEMBL16314611 | 0.78 | ALDH1A1 (0.50) | ALDH1A1TBXAS1EGLN3 | |
| SCHEMBL9276891 | 0.77 | ALDH1A1 (0.46) | ALDH1A1TBXAS1EGLN3 | |
| SCHEMBL10643045 | 0.77 | TBXAS1 (0.48) | ALDH1A1TBXAS1EGLN3 | |
| SCHEMBL28414636 | 0.77 | TBXAS1 (0.56) | ALDH1A1TBXAS1EGLN3ABL1RIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981853-A1 | SUBSTITUTED IMIDAZOLES AND THEIR USE AS PESTICIDES | Pfizer Limited (GB) | 2008-10-22 | — | — | EP | disclosed |
| WO-2007083207-A1 | SUBSTITUTED IMIDAZOLES AND THEIR USE AS PESTICIDES | PFIZER LIMITED (GB) | 2007-07-26 | — | — | WO | disclosed |