Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGER | Q15109 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.51 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.51 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.51 |
| ▸ | QPCT | Q16769 | 1/20 | 0.51 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.51 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11753856 | 0.96 | AGER (0.52) | AGERCYP1A2POLBCYP3A4CYP2D6 | |
| SCHEMBL3690300 | 0.91 | AGER (0.56) | AGERCYP1A2POLBCYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL410696 | 0.90 | AGER (0.55) | AGERCYP1A2POLBCYP3A4CYP2D6 | |
| SCHEMBL8805939 | 0.86 | CYP19A1 (0.63) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL8804766 | 0.86 | CYP2A6 (0.55) | CYP1A2CYP3A4CYP2D6CYP19A1CYP11B1 | |
| SCHEMBL8803211 | 0.86 | CYP19A1 (0.54) | AGERCYP1A2CYP3A4MAPTCYP19A1 | |
| SCHEMBL10642991 | 0.83 | CYP19A1 (0.51) | CYP1A2POLBCYP3A4CYP2D6MAPT | |
| SCHEMBL11281773 | 0.83 | CYP19A1 (0.51) | CYP1A2POLBCYP3A4CYP2D6MAPT | |
| SCHEMBL8803515 | 0.83 | HMOX1 (0.51) | CYP19A1 | |
| SCHEMBL8803553 | 0.83 | CYP3A4 (0.63) | CYP1A2CYP3A4CYP2D6MAPTCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4758573-A | Heterocyclic group-containing compounds | G. D. SEARLE & CO. (US) | 1988-07-19 | — | — | US | disclosed |
| EP-0105575-B1 | 1-(1H-IMIDAZOLYL), 1-N-MORPHOLINYL AND PYRIDYL COMPOUNDS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | G.D. Searle & Co. (US) | 1987-03-04 | — | — | EP | disclosed |
| US-4579862-A | TREATMENT OF CEREBROVASCULAR DISEACE, ISCHEMIA, DIABETES, ANGINA, MYOCARDIAL INFARCTION | G. D. SEARLE & CO. (US) | 1986-04-01 | — | — | US | disclosed |
| EP-0105575-A1 | 1-(1H-imidazolyl), 1-N-morpholinyl and pyridyl compounds, their preparation and pharmaceutical compositions containing them | G.D. Searle & Co. (US) | 1984-04-18 | — | — | EP | disclosed |
| US-4045568-A | FUNGICIDES, BACTERICIDES, ANTIPROTOZOA AGENTS | SYNTEX (U.S.A.) INC. (US) | 1977-08-30 | — | — | US | disclosed |