Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | PGR | P06401 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | SPOP | O43791 | 1/20 | 0.45 |
| ▸ | APAF1 | O14727 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.41 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10643585 | 1.00 | TDP1 (0.56) | TDP1HSD17B10NR1I2TSHRPGR | |
| SCHEMBL11055001 | 0.90 | ABCC4 (0.48) | TDP1HSD17B10NR1I2TSHRPGR | |
| SCHEMBL11055004 | 0.90 | ABCC4 (0.48) | TDP1HSD17B10NR1I2TSHRPGR | |
| SCHEMBL11550663 | 0.86 | TDP1 (0.68) | TDP1HSD17B10NR1I2TSHRPGR | |
| SCHEMBL11332015 | 0.86 | NR1I2 (0.71) | TDP1HSD17B10NR1I2TSHRPGR | |
| SCHEMBL11332011 | 0.86 | NR1I2 (0.71) | TDP1HSD17B10NR1I2TSHRPGR | |
| SCHEMBL11611462 | 0.86 | TDP1 (0.78) | TDP1HSD17B10NR1I2TSHRPGR | |
| SCHEMBL11604888 | 0.86 | TDP1 (0.78) | TDP1HSD17B10NR1I2TSHRPGR | |
| SCHEMBL10649101 | 0.85 | TDP1 (0.41) | TDP1HSD17B10NR1I2TSHRPGR | |
| SCHEMBL10649097 | 0.85 | TDP1 (0.41) | TDP1HSD17B10NR1I2TSHRPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0057422-B1 | NEW CEPHEM COMPOUNDS, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-10-12 | — | — | EP | disclosed |
| EP-0192296-A1 | Novel disaccharide and trisaccharide derivatives of the \"Lipid A\" type | AKZO N.V. (NL) | 1986-08-27 | — | — | EP | disclosed |
| US-4452851-A | BACTERICIDES, ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-06-05 | — | — | US | disclosed |
| EP-0057422-A2 | New cephem compounds, processes for preparation thereof and pharmaceutical composition containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-08-11 | — | — | EP | disclosed |