Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | CES1 | P23141 | 3/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | TNF | P01375 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11607936 | 0.89 | BCL2 (0.43) | MAOAALDH1A1KDM4EMAPTL3MBTL1 | |
| SCHEMBL9182598 | 0.88 | ADORA2A (0.40) | MAOACES1BCHEALDH1A1CYP1A2 | |
| SCHEMBL11037499 | 0.83 | MAOA (0.47) | MAOACES1BCHEALDH1A1CYP1A2 | |
| SCHEMBL4887380 | 0.83 | ALDH1A1 (0.53) | MAOACES1BCHEALDH1A1CYP1A2 | |
| SCHEMBL11140209 | 0.83 | MAOA (0.47) | MAOACES1BCHEALDH1A1CYP1A2 | |
| SCHEMBL1984980 | 0.83 | MAOA (0.47) | MAOACES1BCHECYP1A2HPGD | |
| SCHEMBL11662672 | 0.83 | MAOA (0.47) | MAOACES1BCHEALDH1A1CYP1A2 | |
| SCHEMBL1983880 | 0.83 | TDP1 (0.51) | MAOACES1BCHEALDH1A1CYP1A2 | |
| SCHEMBL23839 | 0.82 | MAOA (0.57) | MAOACES1BCHEALDH1A1CYP1A2 | |
| SCHEMBL8155246 | 0.80 | CA1 (0.46) | MAOACES1BCHEALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4784805-A | DIMERIZATION OR CYCLIZATION IN PRESENCE OF ALKALI METAL HYDROXIDE AND ALIPHATIC ALCOHOL | CIBA-GEIBY CORPORATION (US) | 1988-11-15 | — | — | US | claimed |
| EP-0246193-A2 | Process for the preparation of anthraquinoid intermediate products and vat dyes | CIBA-GEIGY AG (CH) | 1987-11-19 | — | — | EP | claimed |
| US-4784805-A | DIMERIZATION OR CYCLIZATION IN PRESENCE OF ALKALI METAL HYDROXIDE AND ALIPHATIC ALCOHOL | CIBA-GEIBY CORPORATION (US) | 1988-11-15 | — | — | US | disclosed |
| EP-0246193-A2 | Process for the preparation of anthraquinoid intermediate products and vat dyes | CIBA-GEIGY AG (CH) | 1987-11-19 | — | — | EP | disclosed |