Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 10/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 10/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 9/20 | 0.45 |
| ▸ | HTR1A | P08908 | 8/20 | 0.45 |
| ▸ | HTR7 | P34969 | 3/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10643416 | 0.99 | ADRA2A (0.49) | ADRA2AADRA2BALDH1A1MAPTADRA2C | |
| SCHEMBL10756736 | 0.94 | ADRA2A (0.49) | ADRA2AADRA2BALDH1A1MAPTADRA2C | |
| Hydrochloric Acid SCHEMBL10643158 | 0.94 | ADRA2A (0.48) | ADRA2AADRA2BALDH1A1MAPTADRA2C | |
| SCHEMBL10640698 | 0.92 | ADRA2A (0.55) | ADRA2AADRA2BALDH1A1MAPTADRA2C | |
| SCHEMBL10644104 | 0.85 | ADRA2A (0.54) | ADRA2AADRA2BALDH1A1MAPTADRA2C | |
| Hydrochloric Acid SCHEMBL10643422 | 0.84 | ADRA2A (0.53) | ADRA2AADRA2BALDH1A1MAPTADRA2C | |
| SCHEMBL10637602 | 0.83 | ADRA2A (0.64) | ADRA2AADRA2BALDH1A1DRD2DRD3 | |
| SCHEMBL10756741 | 0.79 | ADRA2A (0.53) | ADRA2AADRA2BALDH1A1MAPTADRA2C | |
| SCHEMBL10637728 | 0.79 | HTR7 (0.57) | ADRA2AADRA2BALDH1A1ADRA2CDRD2 | |
| SCHEMBL10642519 | 0.79 | HTR7 (0.57) | ADRA2AADRA2BALDH1A1ADRA2CDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161498-B1 | PHENYLPIPERAZINE DERIVATIVES AND THEIR ACID ADDITION SALTS | MITSUBISHI KASEI CORPORATION (JP) | 1988-10-12 | — | — | EP | disclosed |
| US-4716161-A | HYPOTENSIVE AGENTS | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1987-12-29 | — | — | US | disclosed |