Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.39 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.39 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.39 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.39 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.39 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.39 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.39 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6681802 | 0.80 | L3MBTL1 (0.56) | MAPTTHRATHRBALOX5PTGS2 | |
| SCHEMBL919038 | 0.80 | CYP1A2 (0.58) | MAPTTHRATHRBALOX5PTGS2 | |
| SCHEMBL73826 | 0.79 | CYP1A2 (0.52) | MAPTTHRATHRBALOX5PTGS2 | |
| SCHEMBL31108994 | 0.77 | THRA (0.48) | THRATHRBALOX5PTGS2LTB4R | |
| SCHEMBL11341195 | 0.77 | LTB4R (0.53) | MAPTTHRATHRBALOX5PTGS2 | |
| SCHEMBL16934158 | 0.77 | LTB4R (0.53) | MAPTTHRATHRBALOX5PTGS2 | |
| SCHEMBL9814811 | 0.77 | THRA (0.48) | THRATHRBALOX5PTGS2LTB4R | |
| SCHEMBL11749257 | 0.77 | THRA (0.44) | MAPTTHRATHRBALOX5PTGS2 | |
| SCHEMBL16933732 | 0.77 | LTB4R (0.53) | MAPTTHRATHRBALOX5PTGS2 | |
| SCHEMBL36193 | 0.76 | THRA (0.49) | THRATHRBALOX5PTGS2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1988009782-A1 | PROCESS FOR MAKING PROPARGYL ETHERS OF HYDROXYAROMATIC COMPOUNDS | THE DOW CHEMICAL COMPANY (US) | 1988-12-15 | — | — | WO | disclosed |
| EP-0293768-A1 | Process for making propargyl ethers of hydroxyaromatic compounds | THE DOW CHEMICAL COMPANY (US) | 1988-12-07 | — | — | EP | disclosed |