Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 13/20 | 0.68 |
| ▸ | NT5C2 | P49902 | 2/20 | 0.62 |
| ▸ | NT5E | P21589 | 1/20 | 0.60 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | BRAF | P15056 | 2/20 | 0.50 |
| ▸ | TOP2A | P11388 | 1/20 | 0.50 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29514799 | 0.81 | BRD4 (1.00) | BRD4NT5C2NT5ECREBBPNPC1 | |
| SCHEMBL23124 | 0.81 | BRD4 (1.00) | BRD4NT5C2NT5ECREBBPNPC1 | |
| SCHEMBL10644704 | 0.81 | HPGD (0.44) | BRD4NT5C2NT5ECREBBPNPC1 | |
| SCHEMBL8381776 | 0.80 | BRD4 (0.97) | BRD4NT5C2NT5ECREBBPNPC1 | |
| SCHEMBL6463477 | 0.78 | BRD4 (0.92) | BRD4NT5C2NT5ECREBBPBRAF | |
| SCHEMBL5437612 | 0.76 | BRD4 (0.62) | BRD4NT5C2NT5ECREBBPNPC1 | |
| SCHEMBL9230081 | 0.76 | BRD4 (1.00) | BRD4NT5C2NT5ECREBBPNPC1 | |
| SCHEMBL22118772 | 0.74 | BRD4 (0.68) | BRD4NT5C2NT5ECREBBPNPC1 | |
| SCHEMBL23683051 | 0.73 | CREBBP (1.00) | BRD4NT5C2NT5ECREBBPNPC1 | |
| SCHEMBL536913 | 0.73 | BRAF (0.72) | BRD4NT5C2NT5ECREBBPNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4718936-A | PLANT GROWTH REGULATORS | BASF AKTIENGESELLSCHAFT (DE) | 1988-01-12 | — | — | US | disclosed |
| EP-0154937-A2 | 6-(3-Thienylmethylamino)-purin, process for its preparation and its use | BASF Aktiengesellschaft (DE) | 1985-09-18 | — | — | EP | disclosed |