Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 12/20 | 1.00 |
| ▸ | NT5C2 | P49902 | 2/20 | 0.68 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.66 |
| ▸ | NT5E | P21589 | 1/20 | 0.59 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | KDR | P35968 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5857624 | 0.83 | BRD4 (0.71) | BRD4NT5C2CREBBPMAPTKDR | |
| SCHEMBL29514799 | 0.83 | BRD4 (1.00) | BRD4NT5C2CREBBPNT5ENPC1 | |
| SCHEMBL23124 | 0.83 | BRD4 (1.00) | BRD4NT5C2CREBBPNT5ENPC1 | |
| SCHEMBL8381776 | 0.82 | BRD4 (0.97) | BRD4NT5C2CREBBPNT5ENPC1 | |
| SCHEMBL9230078 | 0.81 | BRD4 (0.68) | BRD4MAPTNPC1RAB9A | |
| SCHEMBL23683051 | 0.80 | CREBBP (1.00) | BRD4NT5C2CREBBPNT5EMKNK1 | |
| SCHEMBL4913787 | 0.78 | RAB9A (0.72) | BRD4MKNK1MAPTNPC1RAB9A | |
| SCHEMBL21401478 | 0.77 | BRD4 (1.00) | BRD4NT5C2CREBBPNT5EMAPT | |
| SCHEMBL29141649 | 0.76 | BRD4 (0.62) | BRD4MKNK1MAPTNPC1RAB9A | |
| SCHEMBL10644711 | 0.76 | BRD4 (0.68) | BRD4NT5C2CREBBPNT5EMKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672661-A1 | Substituted N-ethyl-glycinderivatives for the preparation of PNA and PNA-/DNA hybrides | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-09-20 | — | — | EP | disclosed |