SCHEMBL1064508

SCHEMBL1064508

C=C(C)c1cccc(CO)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRSS1 P07477 1/20 0.55
PRSS2 P07478 1/20 0.55
PRSS3 P35030 1/20 0.55
ENPP2 Q13822 1/20 0.44
TSHR P16473 1/20 0.41
PRKCI P41743 1/20 0.40
CYP4F2 P78329 2/20 0.40
CYP4A11 Q02928 2/20 0.40
SMYD3 Q9H7B4 1/20 0.40
CNR2 P34972 1/20 0.38
MAPT P10636 2/20 0.38
NPC1 O15118 1/20 0.38
TP53 P04637 1/20 0.38
XBP1 P17861 1/20 0.38
HTT P42858 1/20 0.38
RAB9A P51151 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
HSD17B10 Q99714 1/20 0.38
LOXL2 Q9Y4K0 2/20 0.37
FOLH1 Q04609 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7757005 0.84 CYP4F2 (0.57) PRSS1PRSS2PRSS3CYP4F2CYP4A11
SCHEMBL1363307 0.83 BCL2 (0.43) PRSS1PRSS2PRSS3CYP4F2CYP4A11
SCHEMBL608583 0.83 LOXL2 (0.37) PRSS1PRSS2PRSS3TSHRCYP4F2
SCHEMBL16952890 0.83 PRSS1 (0.59) PRSS1PRSS2PRSS3ENPP2TSHR
SCHEMBL27702621 0.82 LOXL2 (0.58) PRSS1PRSS2PRSS3ENPP2SMN1; SMN2
SCHEMBL20919035 0.82 ALDH1A1 (0.39) PRSS1PRSS2PRSS3TSHRCYP4F2
SCHEMBL25955246 0.82 FOLH1 (0.58) PRSS1PRSS2PRSS3CYP4F2CYP4A11
SCHEMBL11600508 0.82 TSHR (0.39) PRSS1PRSS2PRSS3TSHRCYP4F2
SCHEMBL14452916 0.80 PRSS1 (0.52) PRSS1PRSS2PRSS3ENPP2TSHR
SCHEMBL1361055 0.80 KAT6A (0.44) CYP4F2CYP4A11CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024080062-A1 THERMOPLASTIC RESIN COMPOSITION AND MOLDED ARTICLE テクノUMG株式会社 2024-04-18 WO disclosed
US-11866573-B2 Thermoplastic resin composition and molded article TECHNO-UMG CO., LTD. (JP) 2024-01-09 US disclosed
EP-4023726-A1 COATING RESIN COMPOSITION, AND MOLDED PRODUCT Techno-UMG Co., Ltd. (JP) 2022-07-06 EP disclosed
CN-110741043-B Thermoplastic resin composition and molded article 大科能宇菱通株式会社 2022-04-15 CN disclosed
CN-113993955-A Resin composition for coating and molded article 大科能宇菱通株式会社 2022-01-28 CN disclosed
US-11046800-B2 Resin component disposed in route of beam emitted by radar device, radome, and radar device TECHNO-UMG CO., LTD. (JP) 2021-06-29 US disclosed
US-20210087378-A1 THERMOPLASTIC RESIN COMPOSITION AND MOLDED ARTICLE TECHNO-UMG CO., LTD. (JP) 2021-03-25 US disclosed
WO-2021039741-A1 COATING RESIN COMPOSITION, AND MOLDED PRODUCT テクノUMG株式会社 2021-03-04 WO disclosed
CN-108603005-B Resin member disposed on path of beam emitted from radar device, radome, and radar device 大科能宇菱通株式会社 2020-11-03 CN disclosed
US-20200262958-A1 RESIN COMPONENT DISPOSED IN ROUTE OF BEAM EMITTED BY RADAR DEVICE, RADOME, AND RADAR DEVICE TECHNO-UMG CO., LTD. (JP) 2020-08-20 US disclosed
WO-2005026331-A2 METHOD OF PREPARATION OF PHARMACEUTICALLY GRADE PLASMID DNA CENTELION (FR) 2005-03-24 WO disclosed
EP-0964057-B1 Method for separating nucleic acids by means of liquid chromatography TOSOH CORP (JP) 2004-12-22 EP disclosed
US-20040034155-A1 Acenaphthylene derivative, polymer, and antireflection film-forming composition JSR CORPORATION (JP) 2004-02-19 US disclosed
EP-1386904-A1 Acenaphthylene derivative, polymer, and antireflection film-forming composition JSR Corporation (JP) 2004-02-04 EP disclosed
US-6441160-B2 HYDROPHOBIC INTERACTION CHROMATOGRAPHY USING PACKING MATERIAL WITH FUNCTIONAL GROUP INTRODUCED TO ADSORB NUCLEIC ACIDS THAT EXHIBIT CERTAIN HYDROPHOBICITY TOSOH CORPORATION (JP) 2002-08-27 US disclosed
US-20010007026-A1 METHOD OF SEPARATING NUCLEIC ACIDS BY MEANS OF LIQUID CHROMATOGRAPHY TOSOH CORPORATION (JP) 2001-07-05 US disclosed
EP-0964057-A1 Method for separating nucleic acids by means of liquid chromatography TOSOH CORPORATION (JP) 1999-12-15 EP disclosed
US-5234946-A Anticholesterol, antilipemic BANYU PHARMACEUTICAL CO., LTD. (JP) 1993-08-10 US disclosed
EP-0318860-B1 SUBSTITUTED ALKYLAMINE DERIVATIVES BANYU PHARMACEUTICAL CO., LTD. (JP) 1993-06-16 EP disclosed
EP-0318860-A2 Substituted alkylamine derivatives BANYU PHARMACEUTICAL CO., LTD. (JP) 1989-06-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010007026-A1 METHOD OF SEPARATING NUCLEIC ACIDS BY MEANS OF LIQUID CHROMATOGRAPHY DNA2, HNRNPH3, POLRMT PRSS1 1539/4885PRSS2 486/4885PRSS3 621/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.