Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2635792 | 0.71 | HAO1 (0.63) | HDAC1HDAC3HDAC2HDAC8HDAC4 | |
| SCHEMBL10918605 | 0.70 | HDAC1 (0.46) | HDAC1HDAC3HDAC2HDAC8HDAC4 | |
| SCHEMBL21202169 | 0.70 | GSK3B (0.55) | HDAC1HDAC3HDAC2HDAC8HDAC4 | |
| SCHEMBL15551216 | 0.70 | GSK3B (0.47) | HDAC1HDAC3HDAC2HDAC8HDAC4 | |
| SCHEMBL8101844 | 0.69 | KMT2A (0.51) | KMT2AMEN1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL1305020 | 0.69 | GSK3B (0.70) | HDAC1HDAC3HDAC2HDAC8HDAC4 | |
| SCHEMBL16553571 | 0.69 | GSK3B (0.53) | HDAC1HDAC3HDAC2HDAC8HDAC4 | |
| SCHEMBL4770340 | 0.68 | GSK3B (0.57) | HDAC1HDAC3HDAC2HDAC8HDAC4 | |
| SCHEMBL11161484 | 0.67 | KMT2A (0.57) | HDAC1HDAC3HDAC2HDAC8HDAC4 | |
| SCHEMBL7268544 | 0.67 | CES2 (0.43) | HDAC1HDAC3HDAC2HDAC8HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0164101-B1 | BENZOYLPROPIONIC ACID DERIVATIVES, THEIR USE AND PHARMACEUTICAL COMPOSITIONS | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1988-09-07 | — | — | EP | disclosed |