Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 5/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.46 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.44 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10647153 | 0.87 | HDAC1 (0.53) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL10916871 | 0.77 | MAPT (0.52) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL100781 | 0.74 | HDAC1 (0.61) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL6138764 | 0.74 | HDAC1 (0.66) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL3381070 | 0.73 | HDAC8 (0.69) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL7828372 | 0.73 | HDAC8 (0.69) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL2635792 | 0.72 | HAO1 (0.63) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL9622162 | 0.71 | MAPT (0.53) | PLA2G4BHAO1MAPTALDH1A1MEN1 | |
| SCHEMBL100952 | 0.70 | NR4A2 (0.65) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL10645619 | 0.70 | HDAC1 (0.45) | HDAC1HDAC8HDAC3HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4600540-A | &MMUNOLOGY, ANTIARTHRITIC, ANTICARCINOGENIC, BACTERICIDES, ASTHMA | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1986-07-15 | — | — | US | disclosed |
| EP-0164101-A2 | Benzoylpropionic acid derivatives, their use and pharmaceutical compositions | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1985-12-11 | — | — | EP | disclosed |