SCHEMBL10645941

SCHEMBL10645941

CC1(C)CCC(C)(C)c2cc(C=Cc3ccc(O)cc3)ccc21

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 9/20 0.68
RARG P13631 9/20 0.68
RARA P10276 8/20 0.68
CYP26A1 O43174 3/20 0.50
RXRA P19793 3/20 0.48
NQO2 P16083 2/20 0.47
LCK P06239 1/20 0.47
CYP26B1 Q9NR63 1/20 0.46
CYP3A4 P08684 4/20 0.46
KDM4E B2RXH2 3/20 0.46
ALDH1A1 P00352 3/20 0.46
LMNA P02545 3/20 0.46
TP53 P04637 3/20 0.46
CYP1A2 P05177 3/20 0.46
CYP2C19 P33261 3/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
HSD17B10 Q99714 3/20 0.46
CA12 O43570 2/20 0.46
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10645938 1.00 RARB (0.68) RARBRARGRARACYP26A1RXRA
SCHEMBL7548252 0.84 RARB (0.69) RARBRARGRARACYP26A1RXRA
SCHEMBL7548239 0.84 RARB (0.69) RARBRARGRARACYP26A1RXRA
SCHEMBL8458889 0.83 RARA (0.63) RARBRARGRARACYP26A1RXRA
4-Aminophenol SCHEMBL10842270 0.83 RARB (0.79) RARBRARGRARACYP26A1RXRA
4-Aminophenol SCHEMBL10842256 0.83 RARB (0.79) RARBRARGRARACYP26A1RXRA
SCHEMBL8458887 0.83 RARA (0.63) RARBRARGRARACYP26A1RXRA
SCHEMBL13636819 0.83 RARB (0.63) RARBRARGRARACYP26A1RXRA
SCHEMBL10643492 0.81 RARA (0.61) RARBRARGRARANQO2KDM4E
SCHEMBL13636771 0.81 RARB (0.61) RARBRARGRARACYP26A1RXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0232779-B1 VINYL PHENOL DERIVATIVES, THEIR PREPARATION AND THEIR USE BASF Aktiengesellschaft (DE) 1988-10-12 EP disclosed
US-4714786-A Vinylphenol derivatives, their preparation and their use BASF AKTIENGESELLSCHAFT (DE) 1987-12-22 US disclosed
EP-0232779-A1 Vinyl phenol derivatives, their preparation and their use BASF Aktiengesellschaft (DE) 1987-08-19 EP disclosed