Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 9/20 | 0.63 |
| ▸ | RARG | P13631 | 9/20 | 0.63 |
| ▸ | RARA | P10276 | 8/20 | 0.63 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 8/20 | 0.46 |
| ▸ | RXRA | P19793 | 3/20 | 0.44 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7548239 | 0.84 | RARB (0.69) | RARBRARGRARACYP26A1RXRA | |
| SCHEMBL7548252 | 0.84 | RARB (0.69) | RARBRARGRARACYP26A1RXRA | |
| 4-Aminophenol SCHEMBL10842256 | 0.83 | RARB (0.79) | RARBRARGRARACYP26A1RXRA | |
| 4-Aminophenol SCHEMBL10842270 | 0.83 | RARB (0.79) | RARBRARGRARACYP26A1RXRA | |
| SCHEMBL10842264 | 0.83 | RARB (0.63) | RARBRARGRARACYP26A1CYP19A1 | |
| SCHEMBL10645941 | 0.83 | RARB (0.68) | RARBRARGRARACYP26A1CYP19A1 | |
| SCHEMBL10645938 | 0.83 | RARB (0.68) | RARBRARGRARACYP26A1CYP19A1 | |
| SCHEMBL10643492 | 0.81 | RARA (0.61) | RARBRARGRARACYP19A1NQO2 | |
| SCHEMBL13636771 | 0.81 | RARB (0.61) | RARBRARGRARACYP26A1RXRA | |
| SCHEMBL10643499 | 0.81 | RARA (0.61) | RARBRARGRARACYP19A1NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8785001-B2 | Organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2014-07-22 | — | — | US | disclosed |
| US-8304095-B2 | Organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2012-11-06 | — | — | US | disclosed |
| US-20080297037-A1 | Organic Electroluminescent Devices | MERCK PATENT GMBH (DE) | 2008-12-04 | — | — | US | disclosed |
| US-20080272693-A1 | Organic Electroluminescent Devices | MERCK PATENT GMBH (DE) | 2008-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080272693-A1 | Organic Electroluminescent Devices | EML4, MT-ND4L, EPCAM | RARB 1540/4885RARG 2167/4885RARA 2274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.