Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | PLAT | P00750 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9706578 | 0.91 | TSHR (0.34) | TSHRMAPTLMNAHPGDKDM4E | |
| SCHEMBL9706605 | 0.91 | TSHR (0.34) | TSHRMAPTLMNAHPGDKDM4E | |
| SCHEMBL9706613 | 0.89 | PPOX (0.36) | TSHRMAPTLMNAHPGDKDM4E | |
| SCHEMBL10647008 | 0.83 | TSHR (0.36) | TSHRMAPTLMNAHPGDKDM4E | |
| SCHEMBL10645553 | 0.83 | TSHR (0.36) | TSHRMAPTLMNAHPGDKDM4E | |
| SCHEMBL10650046 | 0.81 | TSHR (0.34) | TSHRMAPTLMNAHPGDKDM4E | |
| SCHEMBL10645208 | 0.79 | KDM4E (0.30) | HPGDKDM4EALDH1A1HSD17B10 | |
| SCHEMBL10575094 | 0.77 | PPOX (0.50) | TSHRMAPTLMNAHPGDKDM4E | |
| SCHEMBL9706696 | 0.76 | HPGD (0.38) | TSHRMAPTLMNAHPGDKDM4E | |
| SCHEMBL9706673 | 0.76 | HPGD (0.40) | TSHRMAPTLMNAHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4760163-A | 3-(5-carboxy-4-substituted-phenyl)-(thio)uracil-esters and salts | HOFFMANN-LAROCHE INC. (US) | 1988-07-26 | — | — | US | disclosed |
| US-4746352-A | HERBICIDES | HOFFMANN-LA ROCHE INC. (US) | 1988-05-24 | — | — | US | disclosed |