Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.32 |
| ▸ | IKBKB | O14920 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9706673 | 0.86 | HPGD (0.40) | HPGDTSHRMAPTLMNAALDH1A1 | |
| SCHEMBL9706605 | 0.84 | TSHR (0.34) | HPGDTSHRMAPTLMNAALDH1A1 | |
| SCHEMBL9706536 | 0.84 | HPGD (0.38) | HPGDTSHRMAPTLMNAALDH1A1 | |
| SCHEMBL10646014 | 0.76 | TSHR (0.36) | HPGDTSHRMAPTLMNAALDH1A1 | |
| SCHEMBL10645553 | 0.74 | TSHR (0.36) | HPGDTSHRMAPTLMNAALDH1A1 | |
| SCHEMBL9706578 | 0.74 | TSHR (0.34) | HPGDTSHRMAPTLMNAALDH1A1 | |
| SCHEMBL9706613 | 0.72 | PPOX (0.36) | HPGDTSHRMAPTLMNAALDH1A1 | |
| SCHEMBL10650046 | 0.72 | TSHR (0.34) | HPGDTSHRMAPTLMNAALDH1A1 | |
| SCHEMBL9706593 | 0.70 | TDP1 (0.48) | HPGDTSHRMAPTLMNAALDH1A1 | |
| SCHEMBL9706630 | 0.70 | EPHX2 (0.31) | LMNAALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0195346-B1 | 3-ARYL URACILES AND THEIR USE AS HERBICIDES | CIBA-GEIGY AG (CH) | 1992-06-24 | — | — | EP | claimed |