Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 3/20 | 0.53 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.53 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.53 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 10/20 | 0.44 |
| ▸ | CNR1 | P21554 | 9/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8353837 | 1.00 | PLA2G2A (0.53) | PLA2G2APLA2G10PLA2G1BPLA2G5CNR2 | |
| SCHEMBL8195323 | 1.00 | PLA2G2A (0.53) | PLA2G2APLA2G10PLA2G1BPLA2G5CNR2 | |
| SCHEMBL8356181 | 1.00 | PLA2G2A (0.53) | PLA2G2APLA2G10PLA2G1BPLA2G5CNR2 | |
| SCHEMBL18609340 | 0.94 | PLA2G2A (0.49) | PLA2G2APLA2G10PLA2G1BPLA2G5CNR2 | |
| SCHEMBL8356097 | 0.93 | CNR2 (0.56) | PLA2G2APLA2G10PLA2G1BPLA2G5CNR2 | |
| SCHEMBL8357825 | 0.92 | PLA2G2A (0.59) | PLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL10646140 | 0.90 | PLA2G2A (0.45) | PLA2G2APLA2G10PLA2G1BPLA2G5CNR2 | |
| SCHEMBL497520 | 0.88 | PLA2G2A (0.56) | PLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL9137670 | 0.88 | PLA2G2A (0.56) | PLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL8917115 | 0.88 | PLA2G2A (0.56) | PLA2G2APLA2G10PLA2G1BPLA2G5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5972982-A | CONTAINING 5-TO 9-MEMBERED HETEROARYL MONO- OR BICYCLIC RING SYSTEM HAVING NO MORE THAN 1 CARBONYL CARBON IN THE RING SYSTEM; VIRICIDES, BACTERICIDES | CLARION PHARMACEUTICALS INC. (US) | 1999-10-26 | — | — | US | disclosed |
| EP-0745068-A4 | HETEROARYL-SUBSTITUTED DEOXY GLYCERO-PHOSPHOETHANOLAMINES | CLARION PHARMACEUTICALS INC (US) | 1997-02-26 | — | — | EP | disclosed |
| EP-0745068-A1 | HETEROARYL-SUBSTITUTED DEOXY GLYCERO-PHOSPHOETHANOLAMINES | CLARION PHARMACEUTICALS, INC. (US) | 1996-12-04 | — | — | EP | disclosed |
| WO-1996016041-A1 | HETEROARYL-SUBSTITUTED DEOXY GLYCERO-PHOSPHOETHANOLAMINES | CLARION PHARMACEUTICALS INC. (US) | 1996-05-30 | — | — | WO | disclosed |