Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10648896 | 0.79 | ALDH1A1 (0.42) | ALDH1A1MAPTMAPK1CA12CA9 | |
| SCHEMBL28195508 | 0.76 | ALDH1A1 (0.51) | ALDH1A1MAPTKDM4EHPGDPKM | |
| SCHEMBL10646603 | 0.74 | MMP2 (0.34) | ALDH1A1MAPTKDM4ETDP1AKR1B1 | |
| SCHEMBL4824728 | 0.70 | POLB (0.73) | ALDH1A1KDM4ECA12CA9SMN1; SMN2 | |
| SCHEMBL8973399 | 0.70 | POLB (0.56) | ALDH1A1KDM4ETDP1SMN1; SMN2POLB | |
| SCHEMBL5560749 | 0.66 | KMT2A (0.60) | ALDH1A1MAPTKDM4EHPGDCA12 | |
| SCHEMBL17786550 | 0.66 | CSNK2A2 (0.55) | ALDH1A1MAPTKDM4EHPGDPKM | |
| SCHEMBL2785581 | 0.65 | NPC1 (0.58) | ALDH1A1MAPTKDM4EHPGDTSHR | |
| SCHEMBL15022422 | 0.65 | MCL1 (0.60) | ALDH1A1MAPTKDM4EHPGDPKM | |
| SCHEMBL12325505 | 0.64 | CSNK2A2 (0.51) | ALDH1A1MAPTKDM4EHPGDPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0187387-B1 | BENZOFURAN DERIVATIVE, PROCESS FOR PREPARING THE SAME AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Kaken Pharmaceutical Co., Ltd. (JP) | 1988-09-28 | — | — | EP | claimed |
| EP-0187387-A1 | Benzofuran derivative, process for preparing the same and pharmaceutical composition containing the same | Kaken Pharmaceutical Co., Ltd. (JP) | 1986-07-16 | — | — | EP | claimed |
| EP-0187387-B1 | BENZOFURAN DERIVATIVE, PROCESS FOR PREPARING THE SAME AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Kaken Pharmaceutical Co., Ltd. (JP) | 1988-09-28 | — | — | EP | disclosed |
| EP-0187387-A1 | Benzofuran derivative, process for preparing the same and pharmaceutical composition containing the same | Kaken Pharmaceutical Co., Ltd. (JP) | 1986-07-16 | — | — | EP | disclosed |