⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4945264 | 0.81 | — | — | |
| SCHEMBL13003124 | 0.79 | — | — | |
| SCHEMBL5059682 | 0.79 | ALDH1A1 (0.37) | — | |
| SCHEMBL23384087 | 0.75 | — | — | |
| SCHEMBL26075364 | 0.75 | — | — | |
| SCHEMBL19418536 | 0.75 | — | — | |
| SCHEMBL13497373 | 0.75 | — | — | |
| SCHEMBL9113963 | 0.75 | — | — | |
| SCHEMBL4826277 | 0.75 | — | — | |
| SCHEMBL1061645 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230382932-A1 | Cyclopentane-Based Modulators of STING (Stimulator of Interferon Genes) | PFIZER INC. (US) | 2023-11-30 | — | — | US | disclosed |
| US-20230146410-A1 | CYCLIC DINUCLEOTIDES AS STING AGONISTS | JANSSEN BIOTECH INC (US) | 2023-05-11 | — | — | US | disclosed |
| WO-2022147214-A2 | CYCLIC-DISULFIDE MODIFIED PHOSPHATE BASED OLIGONUCLEOTIDE PRODRUGS | ALNYLAM PHARMACEUTICALS, INC. (US) | 2022-07-07 | — | — | WO | disclosed |
| US-20150190525-A1 | METHODS FOR ARRANGING AND PACKING NUCLEIC ACIDS FOR UNUSUAL RESISTANCE TO NUCLEASES AND TARGETED DELIVERY FOR GENE THERAPY | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-07-09 | — | — | US | disclosed |
| US-8501931-B2 | Convertible nucleoside derivatives | RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) | 2013-08-06 | — | — | US | disclosed |
| US-20120058471-A1 | IDENTIFICATION OF NUCLEIC ACID SEQUENCES | UNIVERSITY OF STRATHCLYDE (GB) | 2012-03-08 | — | — | US | disclosed |
| US-8071737-B2 | Nucleic acid ligand complexes | Glead Sciences, Inc. (US) | 2011-12-06 | — | — | US | disclosed |
| US-20110212030-A1 | Nucleic Acid Ligand Complexes | GILEAD SCIENCES, INC. (US) | 2011-09-01 | — | — | US | disclosed |
| US-7897736-B2 | Fluorescent quenching detecting reagents and methods | ELITECH HOLDING B.V. (NL) | 2011-03-01 | — | — | US | disclosed |
| US-20100179312-A1 | CONVERTIBLE NUCLEOSIDE DERIVATIVES | LAKSHMAN MAHESH K | 2010-07-15 | — | — | US | disclosed |
| US-20100174058-A1 | FLUORESCENT QUENCHING DETECTING REAGENTS AND METHODS | ELITECHGROUP, INC. | 2010-07-08 | — | — | US | disclosed |
| US-20100137614-A1 | NEGATIVELY CHARGED MINOR GROOVE BINDERS | EPOCH BIOSCIENCES, INC. (US) | 2010-06-03 | — | — | US | disclosed |
| US-7662942-B2 | Oligonucleotide probes containing two labels useful in hybridization assays | Elitech Holdings, B.V. (NL) | 2010-02-16 | — | — | US | disclosed |
| US-7582739-B2 | Negatively charged minor groove binders | EPOCH BIOSCIENCES, INC. (US) | 2009-09-01 | — | — | US | disclosed |