Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | LOX | P28300 | 1/20 | 0.30 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.30 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4945264 | 0.86 | — | — | |
| SCHEMBL13060114 | 0.82 | — | — | |
| SCHEMBL4826277 | 0.79 | — | — | |
| SCHEMBL106466 | 0.79 | — | — | |
| SCHEMBL9113963 | 0.79 | — | — | |
| SCHEMBL12730962 | 0.78 | TSHR (0.30) | TSHR | |
| SCHEMBL1500279 | 0.77 | ALDH1A1 (0.41) | ALDH1A1TDP1CYP3A4TSHRLOX | |
| SCHEMBL3503381 | 0.76 | — | — | |
| SCHEMBL7695480 | 0.74 | ALDH1A1 (0.33) | ALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL25025480 | 0.74 | TSHR (0.33) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8193384-B2 | Synthesized using diphosphitylating reagents via solid-phase synthesis; antisense therapy; genetic disorders; anticarcinogenic agents, viricides | Board of Governors for Higher Education, State of Rhode Island and Providence Plantation (US) | 2012-06-05 | — | — | US | disclosed |
| US-8193384-B2 | Synthesized using diphosphitylating reagents via solid-phase synthesis; antisense therapy; genetic disorders; anticarcinogenic agents, viricides | Board of Governors for Higher Education, State of Rhode Island and Providence Plantation (US) | 2012-06-05 | — | — | US | disclosed |
| US-20080207551-A1 | MODIFIED OLIGONUCLEOTIDES CONTAINING DIPHOSPHODIESTER INTERNUCLEOTIDE LINKAGES | BOARD OF GOVERNORS FOR HIGHER EDUCATION, STATE OF RHODE ISLAND AND PROVIDENCE (US) | 2008-08-28 | — | — | US | disclosed |
| US-20080207551-A1 | MODIFIED OLIGONUCLEOTIDES CONTAINING DIPHOSPHODIESTER INTERNUCLEOTIDE LINKAGES | BOARD OF GOVERNORS FOR HIGHER EDUCATION, STATE OF RHODE ISLAND AND PROVIDENCE (US) | 2008-08-28 | — | — | US | disclosed |
| EP-1910394-A2 | MODIFIED OLIGONUCLEOTIDES CONTAINING DIPHOSPHODIESTER INTERNUCLEOTIDE LINKAGES | The Board of Governors for Higher Education State of Rhode Island And Providence Plantations (US) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007030227-A2 | MODIFIED OLIGONUCLEOTIDES CONTAINING DIPHOSPHODIESTER INTERNUCLEOTIDE LINKAGES | THE BOARD OF GOVERNORS FOR HIGHER EDUCATION, (US) | 2007-03-15 | — | — | WO | disclosed |