Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.53 |
| ▸ | MAOA | P21397 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9527473 | 0.85 | KDM4E (0.71) | KDM4ECYP3A4HSD17B10TSHRCYP2C9 | |
| SCHEMBL774316 | 0.85 | KDM4E (0.75) | KDM4ECYP3A4HSD17B10TSHRCYP2C9 | |
| SCHEMBL9527742 | 0.82 | ABCG2 (0.60) | KDM4ECYP3A4HSD17B10TSHRCYP2C9 | |
| SCHEMBL11813859 | 0.80 | KDM4E (0.49) | KDM4ECYP3A4HSD17B10TSHRCYP2C9 | |
| SCHEMBL31723152 | 0.80 | MEN1 (0.72) | KDM4ECYP3A4HSD17B10TSHRABCG2 | |
| SCHEMBL28425332 | 0.80 | MEN1 (0.72) | KDM4ECYP3A4HSD17B10TSHRABCG2 | |
| SCHEMBL4287358 | 0.76 | MAOA (0.59) | KDM4ECYP3A4HSD17B10TSHRCYP2C9 | |
| SCHEMBL15864329 | 0.76 | KDM4E (0.64) | KDM4ECYP3A4HSD17B10TSHRCYP2C9 | |
| SCHEMBL4649956 | 0.75 | KDM4E (0.80) | KDM4ECYP3A4HSD17B10TSHRCYP2C9 | |
| SCHEMBL28824886 | 0.75 | ALDH1A1 (0.70) | KDM4ECYP3A4HSD17B10TSHRCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0290915-A2 | Flavone-3-carboxylic-acid compounds, and process, intermediates for their preparation and medicines containing these compounds | Kali-Chemie Pharma GmbH (DE) | 1988-11-17 | — | — | EP | disclosed |