SCHEMBL774316

SCHEMBL774316

COc1ccc(-c2oc3ccccc3c(=O)c2OC)c(OC)c1OC

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.75
CYP3A4 P08684 5/20 0.75
HSD17B10 Q99714 5/20 0.75
TSHR P16473 3/20 0.75
CYP2C9 P11712 2/20 0.75
CYP2C19 P33261 2/20 0.75
ABCG2 Q9UNQ0 5/20 0.67
MAOA P21397 4/20 0.60
ALDH1A1 P00352 5/20 0.56
MEN1 O00255 4/20 0.56
KMT2A Q03164 4/20 0.56
HPGD P15428 4/20 0.56
ALOX15 P16050 1/20 0.53
HTT P42858 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
NPC1 O15118 2/20 0.51
MAPT P10636 3/20 0.51
LMNA P02545 2/20 0.51
TP53 P04637 1/20 0.51
CASP1 P29466 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1765291 0.89 KDM4E (0.84) KDM4ECYP3A4HSD17B10TSHRCYP2C9
SCHEMBL380906 0.86 KDM4E (1.00) KDM4ECYP3A4HSD17B10TSHRCYP2C9
SCHEMBL10646752 0.85 KDM4E (0.55) KDM4ECYP3A4HSD17B10TSHRCYP2C9
SCHEMBL1764660 0.83 KDM4E (0.56) KDM4ECYP3A4HSD17B10TSHRCYP2C9
SCHEMBL4287358 0.82 MAOA (0.59) KDM4ECYP3A4HSD17B10TSHRCYP2C9
SCHEMBL29993383 0.79 ABCG2 (1.00) KDM4ECYP3A4HSD17B10TSHRCYP2C9
SCHEMBL253523 0.79 ABCG2 (1.00) KDM4ECYP3A4HSD17B10TSHRCYP2C9
SCHEMBL29727380 0.79 KDM4E (0.72) KDM4ECYP3A4HSD17B10TSHRCYP2C9
SCHEMBL8854752 0.79 KDM4E (0.72) KDM4ECYP3A4HSD17B10TSHRCYP2C9
SCHEMBL4649956 0.78 KDM4E (0.80) KDM4ECYP3A4HSD17B10TSHRCYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116268070-A Polyphenol additive capable of improving frozen storage quality of non-rinsed minced fillet and application thereof 中南林业科技大学 2023-06-23 CN claimed
CN-114031951-A Purple bamboo and plum purple red pigment powder and preparation method and application thereof 天津工业大学 2022-02-11 CN claimed
CN-110038054-A Active component improves sleep or antidepression or improves in failure of memory drug or food and applies in preparation in gardenia and branches and leaves fruit 江西中医药大学 2019-07-23 CN claimed
CN-107411083-A Cape jasmine alcohol elution auxiliary improvement of memory capsule or tablet are applied in auxiliary improving memory function health food is prepared 江西中医药大学 2017-12-01 CN claimed
EP-2544554-B1 METHOD FOR STABILIZING WATER INSOLUBLE BIOACTIVE COMPOUND AQUEOUS DISPERSIONS STOKELY VAN CAMP INC (US) 2016-11-30 EP claimed
US-8945646-B2 Method for manufacturing polymethoxyflavones that are highly stable over time and have reduced residual pesticide levels OGAWA & CO., LTD. (JP) 2015-02-03 US claimed
EP-2785204-A1 ZERO CALORIE POLYPHENOL AQUEOUS DISPERSIONS Pepsico, Inc. (US) 2014-10-08 EP claimed
WO-2013082065-A1 ZERO CALORIE POLYPHENOL AQUEOUS DISPERSIONS PEPSICO, INC. (US) 2013-06-06 WO claimed
EP-2544554-A1 METHOD FOR STABILIZING WATER INSOLUBLE BIOACTIVE COMPOUND AQUEOUS DISPERSIONS Stokely-Van Camp, Inc. (US) 2013-01-16 EP claimed
EP-2530080-A1 METHOD FOR MANUFACTURING POLYMETHOXYFLAVONES THAT ARE HIGHLY STABLE OVER TIME AND HAVE REDUCED RESIDUAL PESTICIDE LEVELS Ogawa & Co., Ltd. (JP) 2012-12-05 EP claimed
US-20120301596-A1 METHOD FOR MANUFACTURING POLYMETHOXYFLAVONES THAT ARE HIGHLY STABLE OVER TIME AND HAVE REDUCED RESIDUAL PESTICIDE LEVELS OGAWA & CO LTD (JP) 2012-11-29 US claimed
US-20120070475-A1 Zero Calorie Polyphenol Aqueous Dispersions PEPSICO, INC (US) 2012-03-22 US claimed
US-20110223256-A1 Method For Stabilizing Flavonoid Aqueous Dispersion STOKELY-VAN CAMP, INC. (US) 2011-09-15 US claimed
WO-2011112386-A1 METHOD FOR STABILIZING WATER INSOLUBLE BIOACTIVE COMPOUND AQUEOUS DISPERSIONS STOKELY-VAN CAMP, INC. (US) 2011-09-15 WO claimed
WO-2007070986-A1 FLAVONES ECOBIOTICS LIMITED (AU) 2007-06-28 WO claimed
US-12507703-B2 Methods, devices and compositions for preserving human milk THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2025-12-30 US disclosed
US-20250169516-A1 METHODS, DEVICES AND COMPOSITIONS FOR PRESERVING HUMAN MILK THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2025-05-29 US disclosed
WO-2006127996-A2 COMPOSITIONS AND METHODS FOR OPTIMIZING EXERCISE RECOVERY RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2006-11-30 WO disclosed
EP-0885192-A1 DIHYDROPYRIDINE-, PYRIDINE-, BENZOPYRAN- ONE- AND TRIAZOLOQUINAZOLINE DERIVATIVE, THEIR PREPARATION AND THEIR USE AS ADENOSINE RECEPTOR ANTAGONISTS THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, Department of Health and Human Services (US) 1998-12-23 EP disclosed
WO-1997027177-A2 DIHYDROPYRIDINE-, PYRIDINE-, BENZOPYRAN-4-ONE- AND TRIAZOLOQUINAZOLINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS ADENOSINE RECEPTOR ANTAGONISTS THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1997-07-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12507703-B2 Methods, devices and compositions for preserving human milk LPL, CEL, LPO KDM4E 1457/4885CYP3A4 1678/4885HSD17B10 340/4885
US-20120301596-A1 METHOD FOR MANUFACTURING POLYMETHOXYFLAVONES THAT ARE HIGHLY STABLE OVER TIME AND HAVE REDUCED RESIDUAL PESTICIDE LEVELS VGF, DDT, F2 KDM4E 46/4885CYP3A4 65/4885HSD17B10 2174/4885
US-20120070475-A1 Zero Calorie Polyphenol Aqueous Dispersions FABP4, PGC, FABP6 KDM4E 792/4885CYP3A4 4576/4885HSD17B10 868/4885
US-20110223256-A1 Method For Stabilizing Flavonoid Aqueous Dispersion MLN, NSF, CEL KDM4E 3308/4885CYP3A4 2694/4885HSD17B10 2930/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.