Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.48 |
| ▸ | NPC1 | O15118 | 7/20 | 0.48 |
| ▸ | POLB | P06746 | 4/20 | 0.48 |
| ▸ | CASP3 | P42574 | 2/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.46 |
| ▸ | RELA | Q04206 | 2/20 | 0.46 |
| ▸ | NPY1R | P25929 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30140835 | 0.86 | ALDH1A1 (0.46) | RAB9ANPC1POLBCASP3SENP8 | |
| SCHEMBL2561686 | 0.86 | ALDH1A1 (0.46) | RAB9ANPC1POLBCASP3SENP8 | |
| SCHEMBL22898909 | 0.79 | RAB9A (0.60) | RAB9ANPC1POLBALDH1A1KDM4E | |
| SCHEMBL7834019 | 0.77 | PIM1 (0.55) | RAB9ANPC1POLBCASP3SENP8 | |
| SCHEMBL24522309 | 0.76 | MMP13 (0.55) | RAB9ANPC1CASP3SENP7SENP6 | |
| SCHEMBL22898907 | 0.76 | CYP2A6 (0.51) | RAB9ANPC1POLBCASP3SENP8 | |
| SCHEMBL4387567 | 0.75 | ALDH1A1 (0.74) | RAB9ANPC1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL7836097 | 0.75 | RAB9A (0.53) | RAB9ANPC1POLBALDH1A1KDM4E | |
| SCHEMBL11337269 | 0.74 | ALDH1A1 (0.65) | ALDH1A1KDM4EMAPTCA12CA1 | |
| SCHEMBL14652614 | 0.73 | SMN1; SMN2 (0.51) | RAB9ANPC1POLBCASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0187387-B1 | BENZOFURAN DERIVATIVE, PROCESS FOR PREPARING THE SAME AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Kaken Pharmaceutical Co., Ltd. (JP) | 1988-09-28 | — | — | EP | disclosed |
| EP-0187387-A1 | Benzofuran derivative, process for preparing the same and pharmaceutical composition containing the same | Kaken Pharmaceutical Co., Ltd. (JP) | 1986-07-16 | — | — | EP | disclosed |