Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 6/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CBFB | Q13951 | 4/20 | 0.48 |
| ▸ | METAP2 | P50579 | 3/20 | 0.48 |
| ▸ | METAP1 | P53582 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10679715 | 0.88 | OPRK1 (0.54) | PIN1KMT2AOPRK1KDM4ENPC1 | |
| SCHEMBL11881087 | 0.83 | PIN1 (0.64) | PIN1KMT2AKDM4ENPC1LMNA | |
| Oxalic Acid SCHEMBL28350889 | 0.81 | PIN1 (0.60) | PIN1KMT2AKDM4ENPC1LMNA | |
| SCHEMBL316552 | 0.79 | PIN1 (1.00) | PIN1KDM4EALDH1A1PKMHPGD | |
| SCHEMBL13982947 | 0.79 | KDM4E (0.50) | KMT2AOPRK1KDM4ENPC1LMNA | |
| SCHEMBL28350887 | 0.77 | PIN1 (0.49) | PIN1KMT2AKDM4ENPC1LMNA | |
| SCHEMBL1345968 | 0.77 | KMT2A (0.62) | KMT2AOPRK1KDM4ENPC1LMNA | |
| SCHEMBL28402323 | 0.75 | KMT2A (0.56) | KMT2AOPRK1KDM4ENPC1LMNA | |
| SCHEMBL20665816 | 0.75 | KMT2A (0.56) | KMT2AOPRK1KDM4ENPC1LMNA | |
| SCHEMBL7991915 | 0.75 | TGFBR1 (0.57) | PIN1KMT2AKDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4743586-A | PREPARATION FROM A METHYLAMINE, 2-OXIME OF ETHYL 2,3-DIOXOBUTYRATE, HYDRAZINE, TRIETHOXYMETHANE | AMERICAN CYANAMID COMPANY (US) | 1988-05-10 | — | — | US | disclosed |