Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 8/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 7/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10649044 | 0.94 | ACHE (0.40) | ACHECYP11B1CYP11B2ALOX15MEN1 | |
| SCHEMBL10652461 | 0.91 | CYP19A1 (0.36) | CYP11B1CYP11B2CYP3A4TBXAS1CYP19A1 | |
| SCHEMBL10648690 | 0.83 | CYP11B1 (0.46) | ACHECYP11B1CYP11B2ALOX15MEN1 | |
| Hydrochloric Acid SCHEMBL10651008 | 0.82 | CYP11B1 (0.46) | ACHECYP11B1CYP11B2ALOX15MEN1 | |
| SCHEMBL10648854 | 0.82 | CYP11B1 (0.47) | ACHECYP11B1CYP11B2ALOX15MEN1 | |
| Hydrochloric Acid SCHEMBL10646340 | 0.81 | CYP11B1 (0.46) | ACHECYP11B1CYP11B2ALOX15MEN1 | |
| SCHEMBL10650408 | 0.78 | CYP11B1 (0.45) | ACHECYP11B1CYP11B2ALOX15MEN1 | |
| SCHEMBL10646977 | 0.78 | CYP11B1 (0.45) | ACHECYP11B1CYP11B2ALOX15MEN1 | |
| Hydrochloric Acid SCHEMBL10648154 | 0.77 | CYP11B1 (0.44) | ACHECYP11B1CYP11B2ALOX15MEN1 | |
| SCHEMBL10650460 | 0.75 | CYP11B1 (0.46) | ACHECYP11B1CYP11B2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0128502-B1 | SUBSTITUTED 6-(THIEN-2-YL)-3(2H)-PYRIDAZINONES AND PROCESSES FOR THEIR PREPARATION | A. Nattermann & Cie. GmbH (DE) | 1988-08-31 | — | — | EP | disclosed |