Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 3/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10644355 | 0.81 | MEN1 (0.51) | MEN1PABPC1KMT2AHPGDCA12 | |
| SCHEMBL10643552 | 0.81 | MEN1 (0.48) | MEN1PABPC1KMT2ACA12CA1 | |
| Mitozolomide SCHEMBL97695 | 0.80 | MEN1 (0.64) | MEN1PABPC1KMT2ALMNAALDH1A1 | |
| SCHEMBL3336603 | 0.80 | MEN1 (0.47) | MEN1PABPC1KMT2ACA12CA1 | |
| SCHEMBL3336299 | 0.80 | MEN1 (0.47) | MEN1PABPC1KMT2ACA12CA1 | |
| Water SCHEMBL10648619 | 0.79 | MEN1 (0.46) | MEN1PABPC1KMT2ACA12CA1 | |
| SCHEMBL10648222 | 0.78 | MAPT (0.41) | MEN1PABPC1KMT2ALMNAALDH1A1 | |
| SCHEMBL10646126 | 0.76 | CA12 (0.48) | MEN1PABPC1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL3337129 | 0.74 | MEN1 (0.63) | MEN1PABPC1KMT2ALMNAALDH1A1 | |
| SCHEMBL10648543 | 0.74 | CA12 (0.42) | MEN1PABPC1KMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252682-A2 | Tetrazines | MAY & BAKER LIMITED (GB) | 1988-01-13 | — | — | EP | disclosed |