Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28199041 | 0.85 | HRH3 (0.50) | IRAK4MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL1239870 | 0.82 | MEN1 (0.60) | IRAK4MAPTRAB9AADORA2AADORA1 | |
| SCHEMBL16768775 | 0.81 | IRAK4 (0.48) | IRAK4MAPTRAB9ASMN1; SMN2AGTR1 | |
| SCHEMBL29407960 | 0.81 | IRAK4 (0.48) | IRAK4MAPTRAB9ASMN1; SMN2AGTR1 | |
| Hydrochloric Acid SCHEMBL26616811 | 0.81 | MEN1 (0.58) | IRAK4MAPTRAB9AADORA2AADORA1 | |
| SCHEMBL9073580 | 0.80 | IRAK4 (0.40) | IRAK4RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL8935818 | 0.78 | CCR1 (0.41) | IRAK4MAPTRAB9ASMN1; SMN2POLB | |
| SCHEMBL9256336 | 0.77 | IRAK4 (0.49) | IRAK4GAA | |
| SCHEMBL3721067 | 0.77 | TRPV3 (0.54) | LTA4H | |
| Hydrochloric Acid SCHEMBL8755212 | 0.76 | CCR1 (0.39) | IRAK4MAPTRAB9ASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0114573-B1 | IMIDAZO(1,5-A)PYRIDINE DERIVATIVES | CIBA-GEIGY AG (CH) | 1988-04-20 | — | — | EP | disclosed |
| US-4588732-A | Certain imidazo(1,5-a)pyridine derivatives and their use as thromboxane synthetase inhibitors | CIBA-GEIGY CORPORATION (US) | 1986-05-13 | — | — | US | disclosed |
| EP-0114573-A1 | Imidazo(1,5-a)pyridine derivatives | CIBA-GEIGY AG (CH) | 1984-08-01 | — | — | EP | disclosed |