Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.33 |
| ▸ | DNM2 | P50570 | 7/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | KMT5A | Q9NQR1 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13606383 | 0.92 | DNM2 (0.34) | KCNH2DNM2ALOX15NPSR1 | |
| SCHEMBL13688604 | 0.91 | KDM1A (0.34) | — | |
| SCHEMBL9089687 | 0.88 | CDK1 (0.36) | KCNH2ALOX15 | |
| SCHEMBL10808892 | 0.87 | — | — | |
| SCHEMBL18380651 | 0.86 | TSHR (0.30) | — | |
| SCHEMBL13588272 | 0.86 | CA1 (0.31) | — | |
| SCHEMBL13588271 | 0.85 | ESR1 (0.32) | — | |
| SCHEMBL10650354 | 0.84 | DNM2 (0.32) | DNM2 | |
| SCHEMBL13688602 | 0.82 | CRHR1 (0.36) | — | |
| SCHEMBL18623967 | 0.82 | ALOX15 (0.42) | KCNH2ALOX15ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292437-A2 | Piperidylaminotriazine derivatives and their use as stabilizers | CIBA-GEIGY AG (CH) | 1988-11-23 | — | — | EP | disclosed |