Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TET2 | Q6N021 | 3/20 | 0.44 |
| ▸ | KDM4A | O75164 | 2/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.44 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.44 |
| ▸ | TET3 | O43151 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 13/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | GRM8 | O00222 | 1/20 | 0.43 |
| ▸ | GRM6 | O15303 | 1/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.43 |
| ▸ | GSR | P00390 | 1/20 | 0.43 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.43 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.43 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27877739 | 0.80 | GABRP (0.46) | TET2KDM4AKDM4CKDM2ATET3 | |
| Succinic Acid SCHEMBL28625145 | 0.78 | FOLH1 (0.39) | TET2KDM4AKDM4CKDM2ATET3 | |
| SCHEMBL28969462 | 0.78 | CYP1A2 (0.54) | TET2KDM4AKDM4CKDM2ATET3 | |
| SCHEMBL7054197 | 0.77 | FOLH1 (0.48) | TET2KDM4AKDM4CKDM2ATET3 | |
| SCHEMBL27730939 | 0.77 | CYP1A2 (0.43) | TET2KDM4AKDM4CKDM2ATET3 | |
| SCHEMBL27598470 | 0.77 | CYP1A2 (0.43) | TET2KDM4AKDM4CKDM2ATET3 | |
| SCHEMBL11392156 | 0.76 | TDP1 (0.42) | FOLH1 | |
| SCHEMBL11008799 | 0.76 | TET2 (0.48) | TET2KDM4AKDM4CKDM2ATET3 | |
| Hydrochloric Acid SCHEMBL1268618 | 0.75 | CYP1A2 (0.42) | TET2KDM4AKDM4CKDM2ATET3 | |
| SCHEMBL8080753 | 0.74 | CYP1A2 (0.50) | TET2KDM4AKDM4CKDM2ATET3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170009215-A1 | Transferases and Oxidoreductases, Nucleic Acids Encoding Them and Methods for Making and Using Them | VERENIUM CORPORATION | 2017-01-12 | — | — | US | disclosed |
| US-9399763-B2 | Transferases and oxidoreductases, nucleic acids encoding them and methods for making and using them | BASF ENZYMES LLC (US) | 2016-07-26 | — | — | US | disclosed |
| EP-2238242-B9 | TRANSFERASES AND OXIDOREDUCTASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM | BASF ENZYMES LLC (US) | 2015-06-10 | — | — | EP | disclosed |
| EP-2865750-A2 | Transferases and oxidoreductases, nucleic acids encoding them and methods for making and using them | BASF Enzymes LLC (US) | 2015-04-29 | — | — | EP | disclosed |
| EP-2238242-B1 | TRANSFERASES AND OXIDOREDUCTASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM | VERENIUM CORP (US) | 2014-11-26 | — | — | EP | disclosed |
| US-8785162-B2 | Aminotransferase and oxidoreductase nucleic acids and polypeptides and methods of using | CARGILL, INCORPORATED (US) | 2014-07-22 | — | — | US | disclosed |
| US-20140165221-A1 | Transferases and Oxidoreductases, Nucleic Acids Encoding Them and Methods for Making and Using Them. | VERENIUM CORPORATION (US) | 2014-06-12 | — | — | US | disclosed |
| US-8709772-B2 | Transferases and oxidoreductases, nucleic acids encoding them and methods for making and using them | VERENIUM CORPORATION (US) | 2014-04-29 | — | — | US | disclosed |
| US-20120270281-A1 | BIOREACTOR PERFORMANCE IN THE PRODUCTION OF MONATIN | CARGILL, INCORPORATED (US) | 2012-10-25 | — | — | US | disclosed |
| WO-2011082365-A2 | IMPROVED BIOREACTOR PERFORMANCE IN THE PRODUCTION OF MONATIN | CARGILL, INCORPORATED (US) | 2011-07-07 | — | — | WO | disclosed |
| WO-2011082353-A1 | SEPARATION AND PURIFICATION OF MONATIN | CARGILL, INCORPORATED (US) | 2011-07-07 | — | — | WO | disclosed |
| US-20110033391-A1 | Transferases and Oxidoreductases, Nucleic Acids Encoding them and methods for making and using them | VERENIUM CORPORATION (US) | 2011-02-10 | — | — | US | disclosed |
| US-20110020882-A1 | AMINOTRANSFERASE AND OXIDOREDUCTASE NUCLEIC ACIDS AND POLYPEPTIDES AND METHODS OF USING | CARGILL, INCORPORATED | 2011-01-27 | — | — | US | disclosed |
| EP-2238242-A1 | TRANSFERASES AND OXIDOREDUCTASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM | Verenium Corporation (US) | 2010-10-13 | — | — | EP | disclosed |
| EP-2225390-A1 | AMINOTRANSFERASE AND OXIDOREDUCTASE NUCLEIC ACIDS AND POLYPEPTIDES AND METHODS OF USING | Cargill, Incorporated (US) | 2010-09-08 | — | — | EP | disclosed |
| EP-2194042-A2 | Methods and systems for increasing production of equilibrium reactions | Cargill, Incorporated (US) | 2010-06-09 | — | — | EP | disclosed |
| US-20090198072-A1 | Methods and systems for increasing production of equilibrium reactions | CARGILL, INCORPORATED (US) | 2009-08-06 | — | — | US | disclosed |
| WO-2009088949-A1 | TRANSFERASES AND OXIDOREDUCTASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM | VERENIUM CORPORATION (US) | 2009-07-16 | — | — | WO | disclosed |
| WO-2009088482-A1 | AMINOTRANSFERASE AND OXIDOREDUCTASE NUCLEIC ACIDS AND POLYPEPTIDES AND METHODS OF USING | CARGILL, INCORPORATED (US) | 2009-07-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090198072-A1 | Methods and systems for increasing production of equilibrium reactions | OAT, AADAT, MON2 | TET2 1040/4885KDM4A 4250/4885KDM4C 3863/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.