Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 5/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | GALR3 | O60755 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7280364 | 0.78 | PDE3B (0.48) | KMT2AMEN1CYP1A2LMNAMAPT | |
| SCHEMBL10651151 | 0.67 | PDE3B (0.37) | KMT2AMEN1CYP1A2POLBLMNA | |
| SCHEMBL10648271 | 0.67 | PDE3A (0.59) | KMT2AMEN1CYP1A2POLBLMNA | |
| SCHEMBL13464837 | 0.67 | KMT2A (0.55) | KMT2AMEN1CYP1A2POLBTDP1 | |
| SCHEMBL10648447 | 0.64 | CYP1A2 (0.41) | KMT2AMEN1CYP1A2POLBTDP1 | |
| SCHEMBL10648317 | 0.64 | CYP1A2 (0.39) | KMT2AMEN1CYP1A2POLBLMNA | |
| SCHEMBL10651361 | 0.60 | KMT2A (0.38) | KMT2AMEN1CYP1A2POLBLMNA | |
| SCHEMBL10650151 | 0.60 | CYP1A2 (0.41) | KMT2AMEN1CYP1A2POLBLMNA | |
| SCHEMBL1456606 | 0.60 | CYP1A2 (0.67) | KMT2AMEN1CYP1A2POLBTDP1 | |
| SCHEMBL10645457 | 0.59 | CYP11B1 (0.56) | CYP1A2POLBMAPTPDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0128502-B1 | SUBSTITUTED 6-(THIEN-2-YL)-3(2H)-PYRIDAZINONES AND PROCESSES FOR THEIR PREPARATION | A. Nattermann & Cie. GmbH (DE) | 1988-08-31 | — | — | EP | disclosed |