SCHEMBL106512

SCHEMBL106512

CCO[Si](C)(C)c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.37
ESR2 Q92731 1/20 0.37
LTA4H P09960 1/20 0.35
TP53 P04637 2/20 0.35
ALDH1A1 P00352 2/20 0.35
TSHR P16473 2/20 0.35
KDM4E B2RXH2 1/20 0.35
NPC1 O15118 1/20 0.35
HPGD P15428 1/20 0.35
RAB9A P51151 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
MAPT P10636 1/20 0.33
ELANE P08246 1/20 0.33
RELA Q04206 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
L3MBTL1 Q9Y468 2/20 0.31
KCNH2 Q12809 1/20 0.31
GLA P06280 1/20 0.31
PTGS2 P35354 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27670640 1.00 ESR1 (0.37) ESR1ESR2LTA4HTP53ALDH1A1
SCHEMBL29273131 0.92 ESR1 (0.36) ESR1ESR2LTA4HTP53ALDH1A1
SCHEMBL3124528 0.88 PTGS2 (0.33) ESR1ESR2TP53ALDH1A1TSHR
SCHEMBL704583 0.87 NQO1 (0.33) ESR1
SCHEMBL12727708 0.87 SMN1; SMN2 (0.42) TP53ALDH1A1KDM4ENPC1HPGD
SCHEMBL6749400 0.84 ALDH1A1 (0.41) TP53ALDH1A1TSHRKDM4ESMN1; SMN2
SCHEMBL6751454 0.84 ALDH1A1 (0.41) TP53ALDH1A1TSHRKDM4ESMN1; SMN2
SCHEMBL2950774 0.84 TP53 (0.32) TP53
SCHEMBL8341054 0.83 ESR1 (0.32) ESR1ESR2LTA4HTP53ALDH1A1
SCHEMBL10857927 0.82 CYP3A4 (0.43) ESR1ESR2KDM4EHPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1796 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4592369-A1 UV-CURABLE COATING MATERIAL AND METHOD FOR UV-HARDENING COATING MATERIAL NANO-X GmbH (DE) 2025-07-30 EP claimed
CN-120157885-A Branched methyl phenyl silicone oil and preparation method thereof 辽宁新邦新材料有限公司 2025-06-17 CN claimed
US-12331164-B2 Curable siloxane resin composition KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2025-06-17 US claimed
CN-120005195-A Composition for room temperature vulcanized transparent silicone rubber and preparation method thereof 湖北鑫金鹏新材料有限公司 2025-05-16 CN claimed
CN-119552510-A High-refractive-index low-haze addition type liquid silicone rubber and preparation method thereof 湖北兴瑞硅材料有限公司 2025-03-04 CN claimed
CN-119431794-A Organosilicon tackifier and preparation method and application thereof 杭州之江有机硅化工有限公司 2025-02-14 CN claimed
CN-119144227-A Sandwich breakfast machine surface coating and preparation method thereof 宁波国盛电器有限公司 2024-12-17 CN claimed
CN-119100394-A Method for preparing high-purity nano silicon carbide powder by combining microwave heating technology with self-suspension carbothermal reduction technology 绍兴晶彩科技有限公司 2024-12-10 CN claimed
CN-119100393-A Method for preparing high-purity nano silicon-carbon-oxygen ceramic powder by microwave induction graphite tube-array fluidized bed pyrolysis of silicon-carbon composite aerogel 绍兴晶彩科技有限公司 2024-12-10 CN claimed
CN-118495629-B Silicon paste, organic silicon defoamer composition for pulping black liquor and preparation method of organic silicon defoamer composition 江苏西斯特新材料科技有限公司 2024-10-01 CN claimed
WO-2003026717-A1 NITRIC OXIDE-RELEASING COATED MEDICAL DEVICES AND METHOD OF PREPARING SAME THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2003-04-03 WO claimed
WO-2003027677-A2 METHOD OF ATTACHMENT OF A BIOMOLECULE TO A SOLID SURFACE AMERSHAM BIOSCIENCES UK LIMITED (GB) 2003-04-03 WO claimed
US-6376615-B1 USING FREE RADICALS CENTRO DE INVESTIGACION EN QUIMICA APLICADA (MX) 2002-04-23 US claimed
EP-0742223-B1 A method of preparing a derivative of optically active azetidin-2-one TAKASAGO PERFUMERY CO LTD (JP) 1999-11-17 EP claimed
US-5712388-A Method of preparing a derivative of optically active azetidin-2-one TAKASAGO INTERNATIONAL CORPORATION (JP) 1998-01-27 US claimed
EP-0742223-A1 A method of preparing a derivative of optically active azetidin-2-one Takasago International Corporation (JP) 1996-11-13 EP claimed
EP-0278157-B1 A RUBBER COMPOSITION Shin-Etsu Chemical Co., Ltd. (JP) 1993-06-16 EP claimed
EP-0278157-A2 A rubber composition Shin-Etsu Chemical Co., Ltd. (JP) 1988-08-17 EP claimed
US-4714733-A VULCANIZABLE BLEND OF RUBBER, UNSATURATED POLYSILOXANE, SILICA FILLER, AND THIOCARBAMYL-CONTAINING ORGANOSILANE SHIN-ETSU CHEMICAL CO., LTD. (JP) 1987-12-22 US claimed
US-4455330-A Method of increasing insulation resistance of glass fibers OWENS-CORNING FIBERGLAS CORPORATION (US) 1984-06-19 US claimed