Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | BRD2 | P25440 | 1/20 | 0.30 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17937697 | 0.86 | CYP3A4 (0.35) | CYP3A4 | |
| SCHEMBL15736416 | 0.86 | ACHE (0.38) | — | |
| SCHEMBL8953997 | 0.86 | CYP3A4 (0.47) | TP53CYP3A4 | |
| SCHEMBL17937791 | 0.86 | ALDH1A1 (0.40) | — | |
| SCHEMBL27670640 | 0.84 | ESR1 (0.37) | TP53 | |
| SCHEMBL106512 | 0.84 | ESR1 (0.37) | TP53 | |
| SCHEMBL27031045 | 0.83 | CTSS (0.35) | — | |
| SCHEMBL2957216 | 0.82 | TP53 (0.32) | TP53CYP3A4CYP1A2BRD4BRD2 | |
| SCHEMBL23493464 | 0.82 | TP53 (0.43) | TP53 | |
| SCHEMBL29434597 | 0.82 | TP53 (0.43) | TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100233482-A1 | Organic silicon oxide fine particles and preparation method thereof, porous film-forming composition, porous film and formation method thereof, and semiconductor device | HAMADA YOSHITAKA | 2010-09-16 | — | — | US | disclosed |
| US-7754330-B2 | Organic silicon oxide core-shell particles and preparation method thereof, porous film-forming composition, porous film and formation method thereof, and semiconductor device | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2010-07-13 | — | — | US | disclosed |
| US-20090294726-A1 | ORGANIC SILICON OXIDE FINE PARTICLES AND PREPARATION METHOD THEREOF, POROUS FILM-FORMING COMPOSITION, POROUS FILM AND FORMATION METHOD THEREOF, AND SEMICONDUCTOR DEVICE | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2009-12-03 | — | — | US | disclosed |
| US-20090294922-A1 | ORGANIC SILICON OXIDE FINE PARTICLE AND PREPARATION METHOD THEREOF, POROUS FILM-FORMING COMPOSITION, POROUS FILM AND FORMATION METHOD THEREOF, AND SEMICONDUCTOR DEVICE | PANASONIC CORPORATION (JP) | 2009-12-03 | — | — | US | disclosed |
| EP-0661331-B1 | Silicon-containing polymer, process for preparing the same and monomer thereof | KANEGAFUCHI CHEMICAL IND (JP) | 2001-05-23 | — | — | EP | disclosed |
| EP-0661332-B1 | Silicon-containing reactive polymer and curable resin composition comprising the same | KANEGAFUCHI CHEMICAL IND (JP) | 2000-04-12 | — | — | EP | disclosed |
| US-5691433-A | POLYCARBOSILANES; HEAT RESISTANCE, SOLUBILITY | KANEGAFUCHI CHEMICAL INDUSTRY CO., LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| EP-0661331-A2 | Silicon-containing polymer, process for preparing the same and monomer thereof | Kanegafuchi Chemical Industry Co., Ltd. (JP) | 1995-07-05 | — | — | EP | disclosed |
| EP-0661332-A2 | Silicon-containing reactive polymer and curable resin composition comprising the same | Kanegafuchi Chemical Industry Co., Ltd. (JP) | 1995-07-05 | — | — | EP | disclosed |
| US-3965134-A | Process for making silarylenesilanediol | GENERAL ELECTRIC COMPANY (US) | 1976-06-22 | — | — | US | disclosed |
| US-3959403-A | Process for making silarylenesilanediol, silarylenesiloxanediol and silarylenesiloxane-polydiorganosiloxane block copolymers | GENERAL ELECTRIC COMPANY (US) | 1976-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090294922-A1 | ORGANIC SILICON OXIDE FINE PARTICLE AND PREPARATION METHOD THEREOF, POROUS FILM-FORMING COMPOSITION, POROUS FILM AND FORMATION METHOD THEREOF, AND SEMICONDUCTOR DEVICE | SPOP, OSTC, SEM1 | TP53 1233/4885CYP3A4 2743/4885CYP1A2 2313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.