Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1878847 | 0.81 | TSHR (0.57) | KMT2AMAPTALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL5204610 | 0.78 | RAB9A (0.53) | LMNAKMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL28960849 | 0.74 | LMNA (0.61) | LMNAKMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL13545151 | 0.73 | TRPM8 (0.57) | ALDH1A1SMN1; SMN2CYP3A4CYP1A2CYP2C19 | |
| SCHEMBL7345420 | 0.72 | LMNA (0.50) | LMNAKMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL6964456 | 0.72 | LMNA (0.50) | LMNAKMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL11796918 | 0.72 | MAPT (0.51) | LMNAKMT2AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL12341996 | 0.71 | LMNA (0.52) | LMNAKMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL11713129 | 0.71 | RAB9A (0.52) | LMNAKMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL1744782 | 0.71 | RAB9A (0.66) | LMNAKMT2AMAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0118283-B1 | PHENYL-CYCLOBUTANE CARBOXYLATES AS ARTHROPODICIDES | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1988-11-02 | — | — | EP | claimed |
| US-4044118-A | N-1-HALOMETHYL-1-S-DIALKYLPHOSPHOROTHIOATE METHINYL PHTHALIMIDE ON | TEXACO INC. (US) | 1977-08-23 | — | — | US | disclosed |
| US-3939272-A | 5,6-DIHYDRO-2-METHYL-1,4-OXATHIIN-3-CARBOXYANILIDE-4,4-DIOXIDE, ALKYLATED PHENOL | TEXACO INC. (US) | 1976-02-17 | — | — | US | disclosed |